NPK76-II-72-1 KiNativ -- single dose experiment - Dataset (ID:20106)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
NPK76-II-72-1 PC-3 TLK2
YVAVkIHQLNK
Lys1
-25.5
 10
uM
NPK76-II-72-1 HeLa Wnk1,Wnk2,Wnk3
DLkCDNIFITGPTGSVK
Lys2
-9.3
 10
uM
NPK76-II-72-1 PC-3 Wnk1,Wnk2,Wnk4
IGDLGLATLkR
Activation Loop
-4.5
 10
uM
NPK76-II-72-1 PC-3 WNK4
DLkCDNVFITGPTGSVK
Lys2
3.0
 10
uM
NPK76-II-72-1 HeLa MLTK
WISQDKEVAVKk
Lys1
-31.1
 10
uM
NPK76-II-72-1 PC-3 MLTK
WISQDKEVAVKk
Lys1
-11.3
 10
uM
NPK76-II-72-1 HeLa ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
-16.4
 10
uM
NPK76-II-72-1 PC-3 ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
-1.9
 10
uM
NPK76-II-72-1 HeLa BARK1
DLkPANILLDEHGHVR
Lys2
9.7
 10
uM
NPK76-II-72-1 HeLa BTK
GQYDVAIkMIK
Lys1
-27.4
 10
uM
NPK76-II-72-1 HeLa CAMK1D
LFAVkCIPK
Lys1
17.4
 10
uM
NPK76-II-72-1 PC-3 CDK5
DLkPQNLLINR
Lys2
-13.7
 10
uM
NPK76-II-72-1 HeLa CHK1
DIkPENLLLDER
Lys2
8.8
 10
uM
NPK76-II-72-1 HeLa CHK2
DLkPENVLLSSQEEDCLIK
Lys2
-8.3
 10
uM
NPK76-II-72-1 PC-3 CHK2
DLkPENVLLSSQEEDCLIK
Lys2
1.6
 10
uM
NPK76-II-72-1 HeLa DGKA
IDPVPNTHPLLVFVNPkSGGK
ATP
13.2
 10
uM
NPK76-II-72-1 PC-3 EPHB4
FLEENSSDPTYTSSLGGkIPIR
Activation Loop
-16.7
 10
uM
NPK76-II-72-1 HeLa FES
LRADNTLVAVkSCR
Lys1
3.1
 10
uM
NPK76-II-72-1 HeLa HPK1
DKVSGDLVALkMVK
Lys1
-23.2
 10
uM
NPK76-II-72-1 HeLa IKKE
SGELVAVkVFNTTSYLRPR
Lys1
-6.7
 10
uM
NPK76-II-72-1 HeLa KSR1,KSR2
SkNVFYDNGK
Protein Kinase Domain
-26.5
 10
uM
NPK76-II-72-1 HeLa LATS2
VDTHALYAMkTLR
Lys1
-6.7
 10
uM
NPK76-II-72-1 HeLa LYN
VAVkTLKPGTMSVQAFLEEANLMK
Lys1
-15.2
 10
uM
NPK76-II-72-1 PC-3 M3K2
VYLCYDVDTGRELAVkQVQFDPDSPETSKEVNALECEIQLLK
Lys1
5.7
 10
uM
NPK76-II-72-1 HeLa MAP3K5
DIkGDNVLINTYSGVLK
Lys2
-9.9
 10
uM