NVP-BHG712 KiNativ -- multiple dose experiment - Dataset (ID:20104)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
NVP-BHG712 PC-3 RSK4 domain1
DLkPENILLDEIGHIK
Lys2
17.4
 0.05
uM
NVP-BHG712 PC-3 RSKL1_domain1
VLGVIDkVLLVMDTR
Protein Kinase Domain
-23.0
 0.05
uM
NVP-BHG712 PC-3 SGK3
FYAVkVLQK
Lys1
-7.6
 0.05
uM
NVP-BHG712 PC-3 SLK
ETSVLAAAkVIDTK
Lys1
5.5
 0.05
uM
NVP-BHG712 PC-3 SLK
DLkAGNILFTLDGDIK
Lys2
2.3
 0.05
uM
NVP-BHG712 PC-3 SMG1
DTVTIHSVGGTITILPTKTkPK
ATP
-6.5
 0.05
uM
NVP-BHG712 PC-3 SNRK
DLkPENVVFFEK
Lys2
-4.6
 0.05
uM
NVP-BHG712 PC-3 SRPK1
IIHTDIkPENILLSVNEQYIR
Lys2
10.4
 0.05
uM
NVP-BHG712 PC-3 SRPK1/2
FVAMkVVK
Lys1
21.6
 0.05
uM
NVP-BHG712 PC-3 STLK5
YSVkVLPWLSPEVLQQNLQGYDAK
Activation Loop
-8.7
 0.05
uM
NVP-BHG712 PC-3 STLK5
SVkASHILISVDGK
Lys2
6.0
 0.05
uM
NVP-BHG712 PC-3 STLK6
HTPTGTLVTIkITNLENCNEER
Lys1
-12.3
 0.05
uM
NVP-BHG712 PC-3 STLK6
SIkASHILISGDGLVTLSGLSHLHSLVK
Lys2
-13.9
 0.05
uM
NVP-BHG712 PC-3 MAP3K7,TAK1
DLkPPNLLLVAGGTVLK
Lys2
-7.3
 0.05
uM
NVP-BHG712 PC-3 TAO1,TAOK3
DIkAGNILLTEPGQVK
Lys2
4.2
 0.05
uM
NVP-BHG712 PC-3 TAOK2
DVkAGNILLSEPGLVK
Lys2
1.2
 0.05
uM
NVP-BHG712 PC-3 TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
0.9
 0.05
uM
NVP-BHG712 PC-3 TLK1
YAAVkIHQLNK
Lys1
36.3
 0.05
uM
NVP-BHG712 PC-3 TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-9.9
 0.05
uM
NVP-BHG712 PC-3 TLK2
YVAVkIHQLNK
Lys1
-1.3
 0.05
uM
NVP-BHG712 PC-3 ULK1
DLkPQNILLSNPAGR
Lys2
-15.2
 0.05
uM
NVP-BHG712 PC-3 ULK3
EVVAIKCVAk
Lys1
-6.1
 0.05
uM
NVP-BHG712 PC-3 ULK3
NISHLDLkPQNILLSSLEKPHLK
Lys2
-11.4
 0.05
uM
NVP-BHG712 PC-3 Wnk1,Wnk2,Wnk3
DLkCDNIFITGPTGSVK
Lys2
-16.9
 0.05
uM
NVP-BHG712 PC-3 Wnk1,Wnk2,Wnk4
IGDLGLATLkR
Activation Loop
-20.4
 0.05
uM