JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
JWE-035 HeLa MAP2K6
DVkPSNVLINALGQVK
Lys2
2.6
 10
uM
JWE-035 PC-3 MAP2K6
DVkPSNVLINALGQVK
Lys2
4.3
 10
uM
JWE-035 PC-3 MAP2K6
HVPSGQIMAVkR
Lys1
14.8
 10
uM
JWE-035 HeLa MAP3K1
DVkGANLLIDSTGQR
Lys2
51.1
 10
uM
JWE-035 PC-3 M3K2
ELAVkQVQFDPDSPETSKEVNALECEIQLLK
Lys1
29.8
 10
uM
JWE-035 HeLa M3K2,MAP3K3
DIkGANILR
Lys2
-3.7
 10
uM
JWE-035 PC-3 M3K2,MAP3K3
DIkGANILR
Lys2
25.3
 10
uM
JWE-035 HeLa MAP3K4
DIkGANIFLTSSGLIK
Lys2
1.1
 10
uM
JWE-035 PC-3 MAP3K4
DIkGANIFLTSSGLIK
Lys2
21.0
 10
uM
JWE-035 HeLa MAP3K5,MAP3K6,MAP3K7
IAIkEIPERDSR
Lys1
-2.7
 10
uM
JWE-035 HeLa MARK2,MARK3
DLkAENLLLDADMNIK
Lys2
7.9
 10
uM
JWE-035 PC-3 MARK2,MARK3
DLkAENLLLDADMNIK
Lys2
9.2
 10
uM
JWE-035 HeLa MAST2,MAST4
DLkPDNLLVTSMGHIK
Lys2
6.1
 10
uM
JWE-035 HeLa MAST3
DLkPDNLLITSLGHIK
Lys2
-4.4
 10
uM
JWE-035 PC-3 MAST3
DLkPDNLLITSLGHIK
Lys2
4.3
 10
uM
JWE-035 HeLa MLK3
DLkSNNILLLQPIESDDMEHK
Lys2
12.2
 10
uM
JWE-035 PC-3 MLK3
DLkSNNILLLQPIESDDMEHK
Lys2
15.9
 10
uM
JWE-035 HeLa MPSK1
DLkPTNILLGDEGQPVLMDLGSMNQACIHVEGSR
Lys2
39.4
 10
uM
JWE-035 PC-3 MPSK1
DLkPTNILLGDEGQPVLMDLGSMNQACIHVEGSR
Lys2
68.1
 10
uM
JWE-035 HeLa MSK1,MSK2_domain1
VLGTGAYGkVFLVR
ATP Loop
4.1
 10
uM
JWE-035 HeLa MSK1_domain1
DIkLENILLDSNGHVVLTDFGLSK
Lys2
2.8
 10
uM
JWE-035 HeLa MST1
ETGQIVAIkQVPVESDLQEIIK
Lys1
-3.7
 10
uM
JWE-035 PC-3 MST1
ETGQIVAIkQVPVESDLQEIIK
Lys1
17.1
 10
uM
JWE-035 PC-3 MST1,MST2
DIkAGNILLNTEGHAK
Lys2
-33.0
 10
uM
JWE-035 HeLa MST2
ESGQVVAIkQVPVESDLQEIIK
Lys1
-5.3
 10
uM