XMD11-85h KiNativ -- single dose experiment - Dataset (ID:20098)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD11-85h PC-3 PI4KB
VPHTQAVVLNSkDK
ATP
18.4
 10
uM
XMD11-85h HeLa PIK3C3
TEDGGKYPVIFkHGDDLR
ATP
-5.7
 10
uM
XMD11-85h PC-3 PIK3CB
VFGEDSVGVIFkNGDDLRQDMLTLQMLR
ATP
-82.1
 10
uM
XMD11-85h HeLa PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
-15.1
 10
uM
XMD11-85h PC-3 PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
27.6
 10
uM
XMD11-85h PC-3 PITSLRE
DLkTSNLLLSHAGILK
Lys2
6.3
 10
uM
XMD11-85h PC-3 PKCa,PKCb
DLkLDNVMLDSEGHIK
Lys2
-3.9
 10
uM
XMD11-85h HeLa PKD1,PKD2
NIVHCDLkPENVLLASADPFPQVK
Lys2
4.6
 10
uM
XMD11-85h HeLa PKR
DLkPSNIFLVDTK
Lys2
-0.2
 10
uM
XMD11-85h PC-3 PKR
DLkPSNIFLVDTK
Lys2
0.8
 10
uM
XMD11-85h HeLa PRPK
FLSGLELVkQGAEAR
ATP Loop
-15.2
 10
uM
XMD11-85h PC-3 PRPK
FLSGLELVkQGAEAR
ATP Loop
6.8
 10
uM
XMD11-85h PC-3 ROCK1,ROCK2
DVkPDNMLLDK
Lys2
10.7
 10
uM
XMD11-85h HeLa RSK1,RSK2_domain1
DLkPENILLDEEGHIKLTDFGLSK
Lys2
9.6
 10
uM
XMD11-85h HeLa RSK2_domain1
LTDFGLSkESIDHEKK
Activation Loop
-10.3
 10
uM
XMD11-85h PC-3 RSK2_domain2
DLkPSNILYVDESGNPESIR
Lys2
-3.0
 10
uM
XMD11-85h HeLa RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
-7.8
 10
uM
XMD11-85h PC-3 RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
-2.2
 10
uM
XMD11-85h HeLa RSKL1_domain1
VLGVIDkVLLVMDTR
Protein Kinase Domain
31.3
 10
uM
XMD11-85h HeLa SGK3
FYAVkVLQK
Lys1
-5.3
 10
uM
XMD11-85h HeLa SLK
DLkAGNILFTLDGDIK
Lys2
11.7
 10
uM
XMD11-85h PC-3 SLK
DLkAGNILFTLDGDIK
Lys2
-10.7
 10
uM
XMD11-85h HeLa SMG1
DTVTIHSVGGTITILPTkTKPK
ATP
6.1
 10
uM
XMD11-85h PC-3 SRC
VAIkTLKPGTMSPEAFLQEAQVMK
Lys1
26.3
 10
uM
XMD11-85h HeLa STLK5
YSVkVLPWLSPEVLQQNLQGYDAK
Activation Loop
-30.0
 10
uM