Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. - Dataset (ID:20000)

The original dataset #20000 (LINCS Compound Protein Targets and Concentrations) with kinase inhibitor target information has been replaced with Target Affinity Spectrum binding information for small molecules in the HMS-LINCS database (March 2019).

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HMSL Small Mol Gene ID Binding Class HUGO Gene Symbol
Imatinib
3932
1
LCK
NVP-TAE684
3932
1
LCK
PHA-767491
1859
1
DYRK1A
Saracatinib
3932
1
LCK
R406
3932
1
LCK
ABT-737
572
1
BAD
ABT-737
572
1
BAD
Navitoclax
572
1
BAD
Lestaurtinib
1859
1
DYRK1A
Lestaurtinib
1859
1
DYRK1A
NVP-TAE684
1956
1
EGFR
Masitinib
3932
1
LCK
Fedratinib
3932
1
LCK
Nintedanib
3932
1
LCK
Neratinib
1956
1
EGFR
Neratinib
1956
1
EGFR
Pelitinib
3932
1
LCK
Palbociclib
595
1
CCND1
Palbociclib
595
1
CCND1
PHA-793887
595
1
CCND1
Staurosporine
595
1
CCND1
Staurosporine
595
1
CCND1
Lapatinib
1956
1
EGFR
SB 203580
6300
1
MAPK12
Staurosporine
6300
1
MAPK12