LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)
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| Cell | Small Molecule | Timepoint | GR50 | GRmax | GR_AOC | GEC50 | GRinf | h_GR | r2_GR | pval_GR |
|---|---|---|---|---|---|---|---|---|---|---|
MCF10A-GM_2 | Taxol | 72 | 0.0034 | -0.2221 | 0.7684 | 0.00420 | -0.2170 | 1.6095 | 0.9928 | 1.11022302463e-16 |
MCF10A-GM_1 | Taxol | 72 | 0.0036 | -0.2565 | 0.7506 | 0.00447 | -0.2269 | 1.7041 | 0.9900 | 1.11022302463e-16 |
MCF10A-GM_9 | Taxol | 72 | 0.0037 | -0.2442 | 0.7335 | 0.00470 | -0.2263 | 1.6044 | 0.9924 | 1.11022302463e-16 |
MCF10A-GM_6 | Taxol | 72 | 0.0035 | -0.2324 | 0.7521 | 0.00448 | -0.2160 | 1.4996 | 0.9915 | 1.11022302463e-16 |
MCF10A-GM_3 | Trametinib | 72 | 0.0032 | 0.0891 | 0.6444 | 0.00254 | 0.1236 | 1.1674 | 0.9882 | 1.11022302463e-16 |
MCF10A-GM_6 | Trametinib | 72 | 0.0038 | 0.1052 | 0.6376 | 0.00301 | 0.1167 | 1.2006 | 0.9837 | 1.11022302463e-16 |
MCF10A-GM_2 | Trametinib | 72 | 0.0031 | 0.0932 | 0.6454 | 0.00247 | 0.1261 | 1.2703 | 0.9864 | 1.11022302463e-16 |
MCF10A-GM_1 | Trametinib | 72 | 0.0037 | 0.0635 | 0.6324 | 0.00299 | 0.1133 | 1.2768 | 0.9809 | 1.11022302463e-16 |
MCF10A-GM_4 | Trametinib | 72 | 0.0035 | 0.0966 | 0.6434 | 0.00287 | 0.1094 | 1.2248 | 0.9799 | 1.11022302463e-16 |
MCF10A-GM_5 | Trametinib | 72 | 0.0037 | 0.1008 | 0.6277 | 0.00294 | 0.1274 | 1.3150 | 0.9855 | 1.11022302463e-16 |
MCF10A-GM_9 | Trametinib | 72 | 0.0038 | 0.0688 | 0.6336 | 0.00308 | 0.1142 | 1.3043 | 0.9848 | 1.11022302463e-16 |
MCF10A-GM_8 | Trametinib | 72 | 0.0040 | 0.1027 | 0.6263 | 0.00331 | 0.1110 | 1.2895 | 0.9906 | 1.11022302463e-16 |
MCF10A-GM_7 | Trametinib | 72 | 0.0039 | 0.0719 | 0.6340 | 0.00325 | 0.1062 | 1.3464 | 0.9839 | 1.11022302463e-16 |
MCF10A-GM_9 | Vorinostat | 72 | 1.5617 | 0.0388 | 0.2396 | 1.73350 | -0.0679 | 1.2213 | 0.9929 | 1.11022302463e-16 |
MCF10A-GM_7 | Vorinostat | 72 | 1.5485 | 0.0052 | 0.2515 | 1.79233 | -0.1001 | 1.2484 | 0.9918 | 1.11022302463e-16 |
MCF10A-GM_2 | Vorinostat | 72 | 1.1217 | 0.0167 | 0.2934 | 1.30060 | -0.0891 | 1.1078 | 0.9862 | 1.11022302463e-16 |
MCF10A-GM_5 | Vorinostat | 72 | 1.3313 | 0.0338 | 0.2592 | 1.36448 | -0.0168 | 1.3398 | 0.9902 | 1.11022302463e-16 |
MCF10A-GM_8 | Vorinostat | 72 | 1.4114 | 0.0224 | 0.2573 | 1.60992 | -0.0799 | 1.1262 | 0.9912 | 1.11022302463e-16 |
MCF10A-GM_6 | Vorinostat | 72 | 1.3632 | 0.0467 | 0.2659 | 1.48443 | -0.0521 | 1.1625 | 0.9892 | 1.11022302463e-16 |
MCF10A-GM_4 | Vorinostat | 72 | 1.2988 | 0.0419 | 0.2685 | 1.40992 | -0.0509 | 1.1821 | 0.9889 | 1.11022302463e-16 |
MCF10A-GM_3 | Vorinostat | 72 | 1.1270 | 0.0140 | 0.2901 | 1.24865 | -0.0667 | 1.2227 | 0.9848 | 1.11022302463e-16 |
MCF10A-GM_1 | Vorinostat | 72 | 1.1221 | 0.0197 | 0.2903 | 1.23808 | -0.0618 | 1.1857 | 0.9886 | 1.11022302463e-16 |