LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_8
 Dasatinib 72 0.3362 -0.1510 0.4405 0.46460 -0.1541 0.8309 0.9643
1.11022302463e-16
MCF10A-GM_7
 Vorinostat 72 1.5485 0.0052 0.2515 1.79233 -0.1001 1.2484 0.9918
1.11022302463e-16
MCF10A-GM_2
 Vorinostat 72 1.1217 0.0167 0.2934 1.30060 -0.0891 1.1078 0.9862
1.11022302463e-16
MCF10A-GM_8
 Vorinostat 72 1.4114 0.0224 0.2573 1.60992 -0.0799 1.1262 0.9912
1.11022302463e-16
MCF10A-GM_9
 Vorinostat 72 1.5617 0.0388 0.2396 1.73350 -0.0679 1.2213 0.9929
1.11022302463e-16
MCF10A-GM_3
 Vorinostat 72 1.1270 0.0140 0.2901 1.24865 -0.0667 1.2227 0.9848
1.11022302463e-16
MCF10A-GM_1
 Vorinostat 72 1.1221 0.0197 0.2903 1.23808 -0.0618 1.1857 0.9886
1.11022302463e-16
MCF10A-GM_6
 Vorinostat 72 1.3632 0.0467 0.2659 1.48443 -0.0521 1.1625 0.9892
1.11022302463e-16
MCF10A-GM_4
 Vorinostat 72 1.2988 0.0419 0.2685 1.40992 -0.0509 1.1821 0.9889
1.11022302463e-16
MCF10A-GM_4
 Palbociclib 72 1.0359 0.1030 0.2711 1.08666 -0.0193 0.7905 0.9851
2.44249065418e-15
MCF10A-GM_5
 Vorinostat 72 1.3313 0.0338 0.2592 1.36448 -0.0168 1.3398 0.9902
1.11022302463e-16
MCF10A-GM_9
 Etoposide 72 0.3309 0.0254 0.4307 0.33219 -0.0027 1.3774 0.9906
1.11022302463e-16
MCF10A-GM_3
 Etoposide 72 0.2400 0.0138 0.4788 0.24005 -0.0002 1.2891 0.9909
1.11022302463e-16
MCF10A-GM_4
 Etoposide 72 0.2572 0.0358 0.4719 0.25672 0.0011 1.2747 0.9927
1.11022302463e-16
MCF10A-GM_1
 Etoposide 72 0.2323 0.0175 0.4818 0.23150 0.0024 1.4514 0.9879
1.11022302463e-16
MCF10A-GM_5
 Etoposide 72 0.2715 0.0390 0.4546 0.26956 0.0047 1.3382 0.9912
1.11022302463e-16
MCF10A-GM_2
 Etoposide 72 0.2479 0.0064 0.4665 0.24608 0.0050 1.3936 0.9932
1.11022302463e-16
MCF10A-GM_7
 Etoposide 72 0.3042 0.0190 0.4408 0.30097 0.0071 1.3586 0.9944
1.11022302463e-16
MCF10A-GM_8
 Etoposide 72 0.3062 0.0111 0.4362 0.30305 0.0072 1.4070 0.9958
1.11022302463e-16
MCF10A-GM_6
 Etoposide 72 0.2631 0.0338 0.4508 0.25611 0.0190 1.4355 0.9907
1.11022302463e-16
MCF10A-GM_6
 Palbociclib 72 1.4030 0.2080 0.2525 1.29780 0.0259 0.6833 0.9900
1.11022302463e-16
MCF10A-GM_2
 Palbociclib 72 0.5075 0.1059 0.3396 0.44124 0.0438 0.6549 0.9544
1.88525861589e-11
MCF10A-GM_3
 Neratinib 72 0.2022 0.0710 0.3721 0.18743 0.0439 1.2090 0.8942
1.85039761291e-11
MCF10A-GM_1
 Palbociclib 72 0.3755 0.0386 0.3583 0.32427 0.0472 0.6762 0.9684
9.82769421398e-13
MCF10A-GM_1
 Neratinib 72 0.1969 0.0642 0.3725 0.18049 0.0506 1.2255 0.8983
1.20580212482e-11