LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_6
 Etoposide 72 0.2631 0.0338 0.4508 0.25611 0.0190 1.4355 0.9907
1.11022302463e-16
MCF10A-GM_4
 Etoposide 72 0.2572 0.0358 0.4719 0.25672 0.0011 1.2747 0.9927
1.11022302463e-16
MCF10A-GM_5
 Etoposide 72 0.2715 0.0390 0.4546 0.26956 0.0047 1.3382 0.9912
1.11022302463e-16
MCF10A-GM_7
 Etoposide 72 0.3042 0.0190 0.4408 0.30097 0.0071 1.3586 0.9944
1.11022302463e-16
MCF10A-GM_8
 Etoposide 72 0.3062 0.0111 0.4362 0.30305 0.0072 1.4070 0.9958
1.11022302463e-16
MCF10A-GM_5
 Neratinib 72 0.3531 0.1178 0.2790 0.30699 0.0908 1.4312 0.9264
3.44724249146e-13
MCF10A-GM_6
 Neratinib 72 0.3653 0.1217 0.2764 0.31106 0.1080 1.5128 0.9320
1.43329792479e-13
MCF10A-GM_1
 Palbociclib 72 0.3755 0.0386 0.3583 0.32427 0.0472 0.6762 0.9684
9.82769421398e-13
MCF10A-GM_9
 Etoposide 72 0.3309 0.0254 0.4307 0.33219 -0.0027 1.3774 0.9906
1.11022302463e-16
MCF10A-GM_8
 Neratinib 72 0.4944 0.1601 0.2140 0.38258 0.1735 1.6620 0.9455
1.25455201783e-14
MCF10A-GM_1
 Dasatinib 72 0.2837 -0.1309 0.4667 0.43854 -0.2021 0.7795 0.9729
1.11022302463e-16
MCF10A-GM_2
 Palbociclib 72 0.5075 0.1059 0.3396 0.44124 0.0438 0.6549 0.9544
1.88525861589e-11
MCF10A-GM_8
 Dasatinib 72 0.3362 -0.1510 0.4405 0.46460 -0.1541 0.8309 0.9643
1.11022302463e-16
MCF10A-GM_7
 Neratinib 72 0.6343 0.1902 0.1983 0.47136 0.1837 1.5425 0.9280
2.69895217286e-13
MCF10A-GM_9
 Neratinib 72 0.5877 0.1245 0.2085 0.48257 0.1227 1.4294 0.9393
4.10782519111e-14
MCF10A-GM_5
 Dasatinib 72 0.3227 -0.1921 0.4426 0.48669 -0.1945 0.7999 0.9614
3.33066907388e-16
MCF10A-GM_4
 Dasatinib 72 0.3273 -0.1411 0.4382 0.51788 -0.2003 0.7342 0.9688
1.11022302463e-16
MCF10A-GM_5
 Palbociclib 72 0.8421 0.1400 0.2682 0.57902 0.1419 0.8908 0.9852
2.22044604925e-15
MCF10A-GM_3
 Palbociclib 72 0.6883 0.0974 0.3032 0.58742 0.0550 0.7356 0.9773
6.93889390391e-14
MCF10A-GM_7
 Dasatinib 72 0.3822 -0.1253 0.4260 0.60000 -0.2136 0.7889 0.9676
1.11022302463e-16
MCF10A-GM_2
 Dasatinib 72 0.3007 -0.1486 0.4680 0.61942 -0.3062 0.6611 0.9635
1.11022302463e-16
MCF10A-GM_6
 Dasatinib 72 0.3435 -0.1607 0.4528 0.66326 -0.2814 0.6786 0.9728
1.11022302463e-16
MCF10A-GM_3
 Dasatinib 72 0.3180 -0.1962 0.4706 0.67309 -0.3178 0.6561 0.9749
1.11022302463e-16
MCF10A-GM_9
 Palbociclib 72 1.5113 0.2927 0.2181 0.72834 0.2462 0.9291 0.9902
1.11022302463e-16
MCF10A-GM_8
 Palbociclib 72 1.3076 0.2218 0.2364 0.78812 0.1724 0.8353 0.9515
3.06659142524e-11