LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_4
 Dasatinib 72 0.3273 -0.1411 0.4382 0.51788 -0.2003 0.7342 0.9688
1.11022302463e-16
MCF10A-GM_4
 Etoposide 72 0.2572 0.0358 0.4719 0.25672 0.0011 1.2747 0.9927
1.11022302463e-16
MCF10A-GM_4
 Neratinib 72 0.3333 0.1249 0.2789 0.25439 0.1756 1.6016 0.8850
4.64310812021e-11
MCF10A-GM_4
 Taxol 72 0.0036 -0.2361 0.7531 0.00459 -0.2325 1.5776 0.9936
1.11022302463e-16
MCF10A-GM_4
 Palbociclib 72 1.0359 0.1030 0.2711 1.08666 -0.0193 0.7905 0.9851
2.44249065418e-15
MCF10A-GM_4
 Trametinib 72 0.0035 0.0966 0.6434 0.00287 0.1094 1.2248 0.9799
1.11022302463e-16
MCF10A-GM_4
 Vorinostat 72 1.2988 0.0419 0.2685 1.40992 -0.0509 1.1821 0.9889
1.11022302463e-16
MCF10A-GM_5
 Alpelisib 72 8.5470 0.4318 0.1327 54.70483 -1.0000 0.5918 0.9673
1.11022302463e-16
MCF10A-GM_5
 Dasatinib 72 0.3227 -0.1921 0.4426 0.48669 -0.1945 0.7999 0.9614
3.33066907388e-16
MCF10A-GM_5
 Etoposide 72 0.2715 0.0390 0.4546 0.26956 0.0047 1.3382 0.9912
1.11022302463e-16
MCF10A-GM_5
 Neratinib 72 0.3531 0.1178 0.2790 0.30699 0.0908 1.4312 0.9264
3.44724249146e-13
MCF10A-GM_5
 Taxol 72 0.0035 -0.2405 0.7502 0.00450 -0.2273 1.5202 0.9935
1.11022302463e-16
MCF10A-GM_5
 Palbociclib 72 0.8421 0.1400 0.2682 0.57902 0.1419 0.8908 0.9852
2.22044604925e-15
MCF10A-GM_5
 Trametinib 72 0.0037 0.1008 0.6277 0.00294 0.1274 1.3150 0.9855
1.11022302463e-16
MCF10A-GM_5
 Vorinostat 72 1.3313 0.0338 0.2592 1.36448 -0.0168 1.3398 0.9902
1.11022302463e-16
MCF10A-GM_6
 Alpelisib 72 9.3375 0.4071 0.1347 69.94454 -1.0000 0.5456 0.9466
9.99200722163e-15
MCF10A-GM_6
 Dasatinib 72 0.3435 -0.1607 0.4528 0.66326 -0.2814 0.6786 0.9728
1.11022302463e-16
MCF10A-GM_6
 Etoposide 72 0.2631 0.0338 0.4508 0.25611 0.0190 1.4355 0.9907
1.11022302463e-16
MCF10A-GM_6
 Neratinib 72 0.3653 0.1217 0.2764 0.31106 0.1080 1.5128 0.9320
1.43329792479e-13
MCF10A-GM_6
 Taxol 72 0.0035 -0.2324 0.7521 0.00448 -0.2160 1.4996 0.9915
1.11022302463e-16
MCF10A-GM_6
 Palbociclib 72 1.4030 0.2080 0.2525 1.29780 0.0259 0.6833 0.9900
1.11022302463e-16
MCF10A-GM_6
 Trametinib 72 0.0038 0.1052 0.6376 0.00301 0.1167 1.2006 0.9837
1.11022302463e-16
MCF10A-GM_6
 Vorinostat 72 1.3632 0.0467 0.2659 1.48443 -0.0521 1.1625 0.9892
1.11022302463e-16
MCF10A-GM_7
 Alpelisib 72 11.5543 0.4925 0.1271 7.97966 0.1098 0.6701 0.9498
5.10702591328e-15
MCF10A-GM_7
 Dasatinib 72 0.3822 -0.1253 0.4260 0.60000 -0.2136 0.7889 0.9676
1.11022302463e-16