LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dasatinib | 180622_BG_6 | 4658 | 0.0885 | 111 | 311 | 11 | 3 | Dasatinib | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_3 | 422 | 0.0831 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.05695 | 0.4556 |
| Dasatinib | 180614_BG_04 | 17045 | 0.0174 | 96 | 202 | 9 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 298 | 0.0172 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00281 | 0.9997 |
| Alpelisib | 180614_BG_02 | 16888 | 0.0194 | 31 | 298 | 9 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_2 | 329 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00089 | 0.9954 |
| Etoposide | 180614_BG_03 | 4519 | 0.0341 | 60 | 96 | 8 | 3 | Etoposide | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 156 | 0.0334 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01337 | 0.4645 |
| Neratinib | 180614_BG_03 | 17919 | 0.0179 | 46 | 275 | 13 | 3 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_6 | 321 | 0.0176 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00240 | 1.0233 |
| Etoposide | 180614_BG_04 | 1122 | 0.1804 | 186 | 50 | 4 | 3 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 236 | 0.1738 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.15379 | 0.0561 |
| Neratinib | 180614_BG_02 | 1544 | 0.0852 | 41 | 94 | 10 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_1 | 135 | 0.0804 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06041 | 0.1383 |
| Palbociclib | 180614_BG_02 | 11181 | 0.0199 | 58 | 166 | 6 | 3 | Palbociclib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 224 | 0.0196 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00036 | 0.8114 |
| Alpelisib | 180614_BG_04 | 15464 | 0.0170 | 49 | 215 | 5 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_8 | 264 | 0.0168 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00321 | 0.9546 |
| Neratinib | 180614_BG_04 | 2730 | 0.0411 | 42 | 72 | 7 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_8 | 114 | 0.0401 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02009 | 0.3012 |
| Trametinib | 180614_BG_03 | 2956 | 0.0271 | 28 | 53 | 12 | 3 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 81 | 0.0267 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00668 | 0.3257 |
| Etoposide | 180614_BG_03 | 17346 | 0.0193 | 43 | 292 | 10 | 3 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 335 | 0.0189 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00105 | 1.0080 |
| Trametinib | 180614_BG_04 | 1943 | 0.0585 | 75 | 43 | 8 | 3 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_7 | 118 | 0.0573 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03726 | 0.2014 |
| Alpelisib | 180614_BG_03 | 14508 | 0.0222 | 114 | 211 | 3 | 3 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 325 | 0.0219 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00192 | 0.9255 |
| Dasatinib | 180614_BG_02 | 15955 | 0.0207 | 50 | 281 | 13 | 3 | Dasatinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 331 | 0.0203 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00033 | 0.9690 |
| Alpelisib | 180614_BG_02 | 16699 | 0.0169 | 46 | 237 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 283 | 0.0167 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00333 | 0.9901 |
| Dasatinib | 180614_BG_02 | 17360 | 0.0204 | 53 | 303 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 356 | 0.0201 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00010 | 1.0084 |
| Dasatinib | 180614_BG_04 | 10039 | 0.0320 | 151 | 175 | 6 | 3 | Dasatinib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_8 | 326 | 0.0315 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01146 | 0.7662 |
| Etoposide | 180614_BG_03 | 15513 | 0.0207 | 75 | 247 | 4 | 3 | Etoposide | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 322 | 0.0203 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00034 | 0.9560 |
| Alpelisib | 180614_BG_02 | 12302 | 0.0143 | 23 | 153 | 5 | 3 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_1 | 176 | 0.0141 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00589 | 0.8524 |
| Alpelisib | 180622_BG_7 | 13590 | 0.0234 | 67 | 252 | 3 | 3 | Alpelisib | 0.316033316 | treatment | 72 | 2 | MCF10A-GM_4 | 319 | 0.0229 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00319 | 0.8381 |
| Alpelisib | 180614_BG_03 | 16992 | 0.0167 | 38 | 247 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 285 | 0.0165 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00350 | 0.9983 |
| Dasatinib | 180614_BG_02 | 4298 | 0.0778 | 47 | 291 | 11 | 3 | Dasatinib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_3 | 338 | 0.0729 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05291 | 0.4474 |
| Etoposide | 180622_BG_8 | 784 | 0.1895 | 92 | 74 | 4 | 3 | Etoposide | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_7 | 166 | 0.1747 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.14861 | -0.0129 |
| Etoposide | 180622_BG_8 | 1229 | 0.1412 | 102 | 86 | 3 | 3 | Etoposide | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_7 | 188 | 0.1327 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.10655 | 0.0887 |