LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpelisib | 180703_BG_12 | 21437 | 0.0315 | 58 | 619 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 677 | 0.0306 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00119 | 0.9970 |
Palbociclib | 180614_BG_04 | 2962 | 0.0382 | 74 | 42 | 11 | 20 | Palbociclib | 3.160329361 | treatment | 72 | 1 | MCF10A-GM_9 | 116 | 0.0377 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01769 | 0.3263 |
Neratinib | 180622_BG_8 | 10097 | 0.0176 | 55 | 124 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 2 | MCF10A-GM_9 | 179 | 0.0174 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00871 | 0.7229 |
Neratinib | 180614_BG_04 | 16992 | 0.0211 | 122 | 239 | 14 | 22 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_9 | 361 | 0.0208 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00081 | 0.9983 |
Etoposide | 180703_BG_12 | 1874 | 0.0739 | 114 | 33 | 13 | 12 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_9 | 147 | 0.0727 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.04094 | 0.0788 |
Dasatinib | 180622_BG_8 | 17480 | 0.0299 | 84 | 441 | 9 | 9 | Dasatinib | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_9 | 525 | 0.0292 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.00303 | 0.9418 |