LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

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Small Molecule barcode cell_count frac_dead corpse_count cell_count_dead row column agent concentration role timepoint replicate cell_line dead_count fraction_dead cell_count__time0 dead_count__time0 cell_count__ctrl dead_count__ctrl fraction_dead__ctrl increase_fraction_dead GRvalue
Etoposide
180703_BG_10
 1545 0.0549 58 30 6 22
Etoposide
9.98
treatment
 72 3
MCF10A-GM_2
 88 0.0539 1387.8 74.9 21564 711.9 0.0318 0.02209 0.0275
Trametinib
180614_BG_02
 1792 0.0319 27 31 8 16
Trametinib
0.998
treatment
 72 1
MCF10A-GM_1
 58 0.0314 889.0 105.5 17054 348.0 0.0200 0.01136 0.1788
Vorinostat
180614_BG_03
 2619 0.0368 68 31 9 11
Vorinostat
3.193598006
treatment
 72 1
MCF10A-GM_5
 99 0.0364 889.0 105.5 17054 348.0 0.0200 0.01643 0.2886
Etoposide
180703_BG_10
 1749 0.0332 28 31 10 7
Etoposide
9.98
treatment
 72 3
MCF10A-GM_3
 59 0.0326 1387.8 74.9 21564 711.9 0.0318 0.00083 0.0602
Trametinib
180622_BG_6
 1799 0.0782 119 31 14 14
Trametinib
0.031603332
treatment
 72 2
MCF10A-GM_3
 150 0.0770 832.0 168.3 20016 537.9 0.0261 0.05084 0.1830
Palbociclib
180703_BG_10
 2833 0.0264 45 31 9 10
Palbociclib
10.01326667
treatment
 72 3
MCF10A-GM_2
 76 0.0261 1387.8 74.9 21564 711.9 0.0318 -0.00567 0.1976
Trametinib
180614_BG_03
 1933 0.0547 79 31 7 4
Trametinib
0.031603332
treatment
 72 1
MCF10A-GM_4
 110 0.0538 889.0 105.5 17054 348.0 0.0200 0.03385 0.1999
Trametinib
180622_BG_6
 1783 0.0706 102 31 9 11
Trametinib
0.998
treatment
 72 2
MCF10A-GM_2
 133 0.0694 832.0 168.3 20016 537.9 0.0261 0.04329 0.1807
Trametinib
180614_BG_03
 1896 0.0327 32 31 8 10
Trametinib
0.998
treatment
 72 1
MCF10A-GM_4
 63 0.0322 889.0 105.5 17054 348.0 0.0200 0.01216 0.1945
Vorinostat
180614_BG_04
 1353 0.0946 106 32 12 16
Vorinostat
9.98
treatment
 72 1
MCF10A-GM_9
 138 0.0926 889.0 105.5 17054 348.0 0.0200 0.07256 0.1036
Trametinib
180703_BG_10
 3270 0.0226 43 32 3 20
Trametinib
0.319359801
treatment
 72 3
MCF10A-GM_1
 75 0.0224 1387.8 74.9 21564 711.9 0.0318 -0.00938 0.2418
Trametinib
180614_BG_03
 2649 0.0293 47 32 9 13
Trametinib
0.00998
treatment
 72 1
MCF10A-GM_4
 79 0.0290 889.0 105.5 17054 348.0 0.0200 0.00896 0.2920
Etoposide
180703_BG_11
 1686 0.1069 166 32 14 4
Etoposide
3.193598006
treatment
 72 3
MCF10A-GM_5
 198 0.1051 1387.8 74.9 21564 711.9 0.0318 0.07330 0.0504
Trametinib
180703_BG_12
 3231 0.0309 70 32 8 9
Trametinib
0.099799981
treatment
 72 3
MCF10A-GM_8
 102 0.0306 1387.8 74.9 21564 711.9 0.0318 -0.00120 0.2380
Trametinib
180614_BG_02
 1937 0.0384 43 33 7 12
Trametinib
0.031603332
treatment
 72 1
MCF10A-GM_2
 76 0.0378 889.0 105.5 17054 348.0 0.0200 0.01776 0.2005
Etoposide
180703_BG_12
 1874 0.0739 114 33 13 12
Etoposide
9.98
treatment
 72 3
MCF10A-GM_9
 147 0.0727 1387.8 74.9 21564 711.9 0.0318 0.04094 0.0788
Etoposide
180703_BG_12
 1536 0.0751 89 33 9 8
Etoposide
9.98
treatment
 72 3
MCF10A-GM_7
 122 0.0736 1387.8 74.9 21564 711.9 0.0318 0.04178 0.0260
Trametinib
180703_BG_12
 3264 0.0271 57 33 11 8
Trametinib
0.319359801
treatment
 72 3
MCF10A-GM_9
 90 0.0268 1387.8 74.9 21564 711.9 0.0318 -0.00497 0.2412
Trametinib
180703_BG_10
 2617 0.0297 46 33 8 5
Trametinib
0.319359801
treatment
 72 3
MCF10A-GM_3
 79 0.0293 1387.8 74.9 21564 711.9 0.0318 -0.00250 0.1738
Trametinib
180703_BG_10
 3479 0.0246 53 34 11 10
Trametinib
0.099799981
treatment
 72 3
MCF10A-GM_3
 87 0.0244 1387.8 74.9 21564 711.9 0.0318 -0.00740 0.2614
Trametinib
180703_BG_10
 3116 0.0241 42 34 8 13
Trametinib
0.099799981
treatment
 72 3
MCF10A-GM_2
 76 0.0238 1387.8 74.9 21564 711.9 0.0318 -0.00799 0.2267
Palbociclib
180614_BG_02
 1623 0.0456 42 34 9 10
Palbociclib
10.01326667
treatment
 72 1
MCF10A-GM_2
 76 0.0447 889.0 105.5 17054 348.0 0.0200 0.02474 0.1517
Trametinib
180614_BG_02
 1775 0.0252 11 34 3 20
Trametinib
0.319359801
treatment
 72 1
MCF10A-GM_1
 45 0.0247 889.0 105.5 17054 348.0 0.0200 0.00473 0.1762
Trametinib
180614_BG_03
 1491 0.0576 55 34 8 21
Trametinib
0.998
treatment
 72 1
MCF10A-GM_5
 89 0.0563 889.0 105.5 17054 348.0 0.0200 0.03633 0.1290
Neratinib
180622_BG_6
 1580 0.0770 95 34 10 21
Neratinib
0.997999609
treatment
 72 2
MCF10A-GM_2
 129 0.0755 832.0 168.3 20016 537.9 0.0261 0.04936 0.1500