LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

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Small Molecule barcode cell_count frac_dead corpse_count cell_count_dead row column agent concentration role timepoint replicate cell_line dead_count fraction_dead cell_count__time0 dead_count__time0 cell_count__ctrl dead_count__ctrl fraction_dead__ctrl increase_fraction_dead GRvalue
Trametinib
180614_BG_02
 1685 0.0366 35 28 4 17
Trametinib
0.099799981
treatment
 72 1
MCF10A-GM_1
 63 0.0360 889.0 105.5 17054 348.0 0.0200 0.01605 0.1619
Etoposide
180703_BG_11
 1686 0.1069 166 32 14 4
Etoposide
3.193598006
treatment
 72 3
MCF10A-GM_5
 198 0.1051 1387.8 74.9 21564 711.9 0.0318 0.07330 0.0504
Trametinib
180622_BG_6
 1686 0.0937 128 42 7 12
Trametinib
0.031603332
treatment
 72 2
MCF10A-GM_2
 170 0.0916 832.0 168.3 20016 537.9 0.0261 0.06547 0.1664
Neratinib
180622_BG_6
 1691 0.0642 68 45 11 20
Neratinib
0.997999609
treatment
 72 2
MCF10A-GM_3
 113 0.0626 832.0 168.3 20016 537.9 0.0261 0.03651 0.1672
Trametinib
180622_BG_6
 1705 0.0800 96 48 8 5
Trametinib
0.319359801
treatment
 72 2
MCF10A-GM_3
 144 0.0779 832.0 168.3 20016 537.9 0.0261 0.05176 0.1693
Etoposide
180703_BG_12
 1707 0.0508 63 27 12 4
Etoposide
3.193598006
treatment
 72 3
MCF10A-GM_9
 90 0.0501 1387.8 74.9 21564 711.9 0.0318 0.01828 0.0537
Etoposide
180703_BG_11
 1710 0.1078 182 22 14 16
Etoposide
9.98
treatment
 72 3
MCF10A-GM_6
 204 0.1066 1387.8 74.9 21564 711.9 0.0318 0.07478 0.0542
Neratinib
180622_BG_8
 1714 0.0704 47 77 13 14
Neratinib
3.160329364
treatment
 72 2
MCF10A-GM_9
 124 0.0675 832.0 168.3 20016 537.9 0.0261 0.04134 0.1706
Etoposide
180703_BG_11
 1724 0.0998 149 38 4 13
Etoposide
9.98
treatment
 72 3
MCF10A-GM_4
 187 0.0979 1387.8 74.9 21564 711.9 0.0318 0.06606 0.0563
Trametinib
180622_BG_8
 1729 0.0463 42 40 11 8
Trametinib
0.319359801
treatment
 72 2
MCF10A-GM_9
 82 0.0453 832.0 168.3 20016 537.9 0.0261 0.01915 0.1728
Taxol
180703_BG_11
 1739 0.7248 677 1074 5 16
Paclitaxel
0.00998
treatment
 72 3
MCF10A-GM_4
 1751 0.5017 1387.8 74.9 21564 711.9 0.0318 0.46992 0.0587
Trametinib
180622_BG_8
 1740 0.0595 59 48 8 13
Trametinib
0.319359801
treatment
 72 2
MCF10A-GM_8
 107 0.0579 832.0 168.3 20016 537.9 0.0261 0.03181 0.1744
Etoposide
180622_BG_8
 1742 0.0793 61 82 10 12
Etoposide
0.997999808
treatment
 72 2
MCF10A-GM_8
 143 0.0759 832.0 168.3 20016 537.9 0.0261 0.04974 0.1747
Etoposide
180703_BG_10
 1749 0.0332 28 31 10 7
Etoposide
9.98
treatment
 72 3
MCF10A-GM_3
 59 0.0326 1387.8 74.9 21564 711.9 0.0318 0.00083 0.0602
Trametinib
180614_BG_02
 1751 0.0322 18 39 9 11
Trametinib
0.998
treatment
 72 1
MCF10A-GM_2
 57 0.0315 889.0 105.5 17054 348.0 0.0200 0.01153 0.1724
Trametinib
180614_BG_02
 1752 0.0570 39 63 6 4
Trametinib
0.031603332
treatment
 72 1
MCF10A-GM_1
 102 0.0550 889.0 105.5 17054 348.0 0.0200 0.03502 0.1726
Vorinostat
180703_BG_11
 1752 0.1601 234 84 5 17
Vorinostat
9.98
treatment
 72 3
MCF10A-GM_5
 318 0.1536 1387.8 74.9 21564 711.9 0.0318 0.12182 0.0606
Dasatinib
180622_BG_6
 1758 0.1826 109 232 13 9
Dasatinib
3.193598006
treatment
 72 2
MCF10A-GM_3
 341 0.1625 832.0 168.3 20016 537.9 0.0261 0.13633 0.1771
Trametinib
180622_BG_8
 1759 0.0698 76 52 6 20
Trametinib
0.998
treatment
 72 2
MCF10A-GM_7
 128 0.0678 832.0 168.3 20016 537.9 0.0261 0.04171 0.1772
Etoposide
180703_BG_11
 1760 0.0979 161 27 14 17
Etoposide
3.193598006
treatment
 72 3
MCF10A-GM_6
 188 0.0965 1387.8 74.9 21564 711.9 0.0318 0.06471 0.0619
Neratinib
180622_BG_8
 1764 0.0705 67 62 4 22
Neratinib
3.160329364
treatment
 72 2
MCF10A-GM_7
 129 0.0681 832.0 168.3 20016 537.9 0.0261 0.04202 0.1780
Neratinib
180614_BG_03
 1766 0.0627 53 61 9 8
Neratinib
0.997999609
treatment
 72 1
MCF10A-GM_5
 114 0.0606 889.0 105.5 17054 348.0 0.0200 0.04064 0.1748
Palbociclib
180614_BG_02
 1772 0.0526 54 42 6 15
Palbociclib
3.160329361
treatment
 72 1
MCF10A-GM_2
 96 0.0514 889.0 105.5 17054 348.0 0.0200 0.03140 0.1757
Trametinib
180614_BG_02
 1775 0.0252 11 34 3 20
Trametinib
0.319359801
treatment
 72 1
MCF10A-GM_1
 45 0.0247 889.0 105.5 17054 348.0 0.0200 0.00473 0.1762
Dasatinib
180622_BG_6
 1778 0.1612 65 232 12 3
Dasatinib
3.193598006
treatment
 72 2
MCF10A-GM_2
 297 0.1431 832.0 168.3 20016 537.9 0.0261 0.11701 0.1800