LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180614_BG_03 | 17461 | 0.0174 | 55 | 249 | 13 | 15 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 304 | 0.0171 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00288 | 1.0111 |
| Etoposide | 180614_BG_03 | 1329 | 0.1005 | 74 | 67 | 8 | 5 | Etoposide | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_6 | 141 | 0.0959 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07592 | 0.0989 |
| Etoposide | 180614_BG_03 | 1152 | 0.1158 | 100 | 45 | 7 | 16 | Etoposide | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_5 | 145 | 0.1118 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.09180 | 0.0627 |
| Dasatinib | 180614_BG_03 | 14695 | 0.0177 | 72 | 189 | 8 | 18 | Dasatinib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 261 | 0.0175 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00254 | 0.9313 |
| Etoposide | 180614_BG_03 | 1121 | 0.1732 | 149 | 71 | 3 | 8 | Etoposide | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_4 | 220 | 0.1641 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.14406 | 0.0559 |
| Alpelisib | 180614_BG_03 | 12582 | 0.0207 | 79 | 183 | 4 | 9 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_4 | 262 | 0.0204 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00040 | 0.8623 |
| Palbociclib | 180614_BG_03 | 4268 | 0.0344 | 90 | 60 | 6 | 6 | Palbociclib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_4 | 150 | 0.0340 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01396 | 0.4450 |
| Dasatinib | 180614_BG_03 | 14962 | 0.0173 | 73 | 187 | 6 | 15 | Dasatinib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_5 | 260 | 0.0171 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00291 | 0.9395 |
| Taxol | 180614_BG_03 | 428 | 1.0167 | 291 | 440 | 11 | 17 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_5 | 731 | 0.6307 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.61072 | -0.1576 |
| Taxol | 180614_BG_03 | 457 | 0.9960 | 301 | 454 | 14 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_6 | 755 | 0.6229 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.60294 | -0.1445 |
| Etoposide | 180614_BG_03 | 4408 | 0.0377 | 71 | 98 | 11 | 7 | Etoposide | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_6 | 169 | 0.0369 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01693 | 0.4560 |
| Etoposide | 180614_BG_03 | 4519 | 0.0341 | 60 | 96 | 8 | 3 | Etoposide | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 156 | 0.0334 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01337 | 0.4645 |
| Etoposide | 180614_BG_03 | 4731 | 0.0315 | 59 | 92 | 9 | 7 | Etoposide | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_5 | 151 | 0.0309 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01093 | 0.4803 |
| Dasatinib | 180614_BG_03 | 14348 | 0.0240 | 119 | 228 | 3 | 7 | Dasatinib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_4 | 347 | 0.0236 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00362 | 0.9205 |
| Alpelisib | 180614_BG_03 | 16397 | 0.0156 | 59 | 198 | 6 | 7 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_5 | 257 | 0.0154 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00456 | 0.9816 |
| Taxol | 180614_BG_03 | 738 | 0.8292 | 263 | 567 | 9 | 10 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_5 | 830 | 0.5293 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.50934 | -0.0427 |
| Taxol | 180614_BG_03 | 707 | 0.7021 | 206 | 435 | 4 | 16 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_4 | 641 | 0.4755 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.45552 | -0.0523 |
| Taxol | 180614_BG_03 | 688 | 0.7478 | 208 | 462 | 10 | 14 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_6 | 670 | 0.4934 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.47338 | -0.0584 |
| Etoposide | 180614_BG_03 | 9835 | 0.0212 | 54 | 156 | 11 | 20 | Etoposide | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_6 | 210 | 0.0209 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00091 | 0.7577 |
| Etoposide | 180614_BG_03 | 10451 | 0.0232 | 89 | 156 | 11 | 16 | Etoposide | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_5 | 245 | 0.0229 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00291 | 0.7829 |
| Taxol | 180614_BG_03 | 429 | 1.0726 | 287 | 481 | 10 | 22 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_4 | 768 | 0.6416 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.62161 | -0.1571 |
| Etoposide | 180614_BG_03 | 9880 | 0.0215 | 98 | 117 | 7 | 14 | Etoposide | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_4 | 215 | 0.0213 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00130 | 0.7596 |
| Dasatinib | 180614_BG_03 | 16537 | 0.0134 | 64 | 159 | 9 | 15 | Dasatinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 223 | 0.0133 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00669 | 0.9856 |
| Dasatinib | 180614_BG_03 | 15704 | 0.0164 | 52 | 206 | 8 | 20 | Dasatinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 258 | 0.0162 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00383 | 0.9617 |
| Alpelisib | 180614_BG_03 | 14611 | 0.0183 | 73 | 196 | 6 | 17 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_6 | 269 | 0.0181 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00192 | 0.9287 |