Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
MDA-MB-468 Doxorubicin
Chemo
Chemotherapy
0.0054214
 -0.3392 0.9121 0.3191 2.4137
0.0067542
0.99424
HCC38 Taxol
Chemo
Chemotherapy
0.0014659
 -0.3078 0.8432 0.2758 2.3201
0.0017274
0.99328
HCC70 Cisplatin
Chemo
Chemotherapy
1.3073
 -0.6832 0.2650 0.0820 1.3165
3.0116
0.99076
MCF7 Taxol
Chemo
Chemotherapy
0.0013771
 -0.1059 0.7722 0.1589 1.1560
0.0016261
0.94939
MCF7 Doxorubicin
Chemo
Chemotherapy
0.016105
 -0.2856 0.6363 0.1012 0.9326
0.024539
0.97476
CAL-51 Taxol
Chemo
Chemotherapy
0.004167
 -0.2200 0.6694 0.1963 1.3689
0.0053072
0.99639
MCF7 Cisplatin
Chemo
Chemotherapy
9.3237
 0.4749 0.0631 0.0037 1.0987
15.5357
0.99433
HCC1143 Taxol
Chemo
Chemotherapy
0.0020688
 -0.3349 0.8388 0.3074 2.5955
0.0024565
0.99279
MDA-MB-453 Cisplatin
Chemo
Chemotherapy
3.4106
 0.1328 0.0938 -0.0013 3.0256
3.151
0.9887
MDA-MB-361 Taxol
Chemo
Chemotherapy
0.0031082
 -0.6090 0.9738 0.2561 2.5508
0.0042111
0.9201
BT-20 Taxol
Chemo
Chemotherapy
0.0020158
 -0.5760 0.9854 0.4456 2.0677
0.0028795
0.99355
BT-20 Doxorubicin
Chemo
Chemotherapy
0.0087386
 -0.4813 0.8279 0.3024 1.4443
0.013048
0.9861
BT-20 Cisplatin
Chemo
Chemotherapy
0.79098
 -0.3367 0.3338 0.0794 0.9579
1.7289
0.98666
HCC1806 Cisplatin
Chemo
Chemotherapy
0.82764
 -0.3648 0.3231 0.1009 1.1777
1.5296
0.98889
HCC70 Doxorubicin
Chemo
Chemotherapy
0.010621
 -0.7794 0.7867 0.1459 2.0410
0.014138
0.93856
HCC1143 Doxorubicin
Chemo
Chemotherapy
0.0092688
 -0.2511 0.7180 0.1402 1.1622
0.012302
0.98917
MDA-MB-453 Doxorubicin
Chemo
Chemotherapy
0.0058313
 -0.3476 0.7915 0.1805 1.7510
0.0071438
0.98132
HCC1937 Taxol
Chemo
Chemotherapy
0.0024514
 0.0104 0.6576 0.2104 2.2541
0.0024561
0.99541
HCC38 Doxorubicin
Chemo
Chemotherapy
0.0095452
 -0.4061 0.7803 0.2872 1.4810
0.01343
0.99228
BT-549 Taxol
Chemo
Chemotherapy
0.0027257
 -0.2074 0.6989 0.2304 1.9420
0.0030953
0.98743
PDX1258 Taxol
Chemo
Chemotherapy
0.0021522
 -0.0818 0.6797 0.2357 1.2501
0.0022935
0.98829
PDX1328 Doxorubicin
Chemo
Chemotherapy
0.013267
 -0.7789 0.8023 0.1468 1.4934
0.021574
0.96338
HCC1806 Doxorubicin
Chemo
Chemotherapy
0.015898
 -0.3241 0.6281 0.1971 1.0948
0.021206
0.97525
CAL-51 Doxorubicin
Chemo
Chemotherapy
0.0085841
 -0.4803 0.7954 0.2347 1.0881
0.014188
0.98761
MDA-MB-134-VI Taxol
Chemo
Chemotherapy
0.00012515
 -0.7183 1.3004 0.3511 0.5352
0.00075273
0.89205