Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

 Full screen view
Filter results: >>>>
Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
PDXHCI002 Cediranib
VEGFR/cKIT
RTK
1.4694
 -0.4324 0.2592 0.0666 0.9820
4.4977
0.98683
PDXHCI002 Cabozantinib
VEGFR2/MET
RTK
7.2097
 0.2341 0.0443 0.0248 1.8969
12.8614
0.98302
HCC1428 Tivantinib
MET
RTK
0.2516
 0.0341 0.3664 0.1106 2.2041
0.23715
0.99573
SK-BR-3 Cabozantinib
VEGFR2/MET
RTK
9.7073
 0.4422 0.0013 0.0011 5.0000
12.0523
0.95604
SK-BR-3 Cediranib
VEGFR/cKIT
RTK
6.1955
 -0.5397 0.0755 0.0528 4.8242
7.7773
0.99548
SK-BR-3 Tivantinib
MET
RTK
0.27263
 -0.3523 0.4830 0.2060 2.4177
0.34098
0.99571
SK-BR-3 Neratinib
EGFR/HER2
RTK
0.0016518
 -0.2530 0.8909 0.2029 0.7723
0.0025421
0.9721
SK-BR-3 Ceritinib
ALK
RTK
0.98319
 -0.8254 0.3174 0.0975 1.2454
2.3754
0.98337
HCC1428 Cediranib
VEGFR/cKIT
RTK
3.1657
 -0.5502 0.1943 0.0619 1.9637
5.5392
0.98192
MDA-MB-361 Neratinib
EGFR/HER2
RTK
0.15196
 -0.5277 0.4246 0.0772 0.5626
1.0709
0.91404
CAL-120 Ceritinib
ALK
RTK
0.79939
 -0.4322 0.3366 0.1170 1.0290
1.7983
0.99115
CAL-120 Neratinib
EGFR/HER2
RTK
0.59003
 -0.2607 0.2238 0.0655 0.9310
1.9202
0.98923
CAL-120 Tivantinib
MET
RTK
0.25132
 -0.2562 0.4649 0.1572 1.1267
0.37355
0.99876
CAL-120 Cediranib
VEGFR/cKIT
RTK
1.037
 -0.1243 0.2989 0.0564 0.5757
6.9922
0.99099
CAL-120 Cabozantinib
VEGFR2/MET
RTK
7.3417
 0.2574 0.0848 0.0071 1.8478
13.277
0.98262