Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

 Full screen view
Filter results: >>>>
Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
T47D Vorinostat
HDAC
Misc
1.8007
 -0.1567 0.1750 0.0409 2.2684
2.0704
0.99157
T47D ABT-737
Bcl2/XL
Misc
12.2023
 0.5888 0.0010 0.0084 2.2890
9.7541
0.92156
T47D Saracatinib
SRC
MAPK/nRTK
3.9647
 0.3892 0.1722 0.0087 0.6928
1.6318
0.9752
T47D Trametinib
MEK
MAPK/nRTK
Inf
 0.5801 0.2130 0.0041 0.9941
0.0048584
0.90394
T47D Dasatinib
BCR/ABL
MAPK/nRTK
12.5697
 0.4961 0.1933 0.0086 0.2753
679.7315
0.95229
T47D Etoposide
Topo II
Chemotherapy
0.041662
 -0.1861 0.6661 0.0533 1.1976
0.051932
0.98563
T47D Topotecan
Topo I
Chemotherapy
0.0052275
 -0.1971 0.9594 0.1261 1.3094
0.0068541
0.99083
T47D Taxol
Chemo
Chemotherapy
0.0035285
 -0.1337 0.6636 0.2505 2.2353
0.0038792
0.99665
T47D Doxorubicin
Chemo
Chemotherapy
0.0018887
 -0.3611 0.9189 0.1014 1.2268
0.0024801
0.96538
T47D Cisplatin
Chemo
Chemotherapy
1.5698
 0.1019 0.2147 0.0055 1.3290
1.5705
0.98121
T47D Dinaciclib
pan CDK
Cell cycle
0.019853
 -0.2109 0.4815 0.0484 5.0000
0.021113
0.99494
T47D Volasertib
PLK
Cell cycle
0.031411
 -0.1585 0.3959 0.0580 1.7544
0.036365
0.99393
T47D AZD7762
CHK1/2
Cell cycle
2.3432
 -0.0573 0.1322 0.0195 2.6709
2.4809
0.98871
T47D Palbociclib
CDK4/6
Cell cycle
0.027507
 0.1166 0.4501 0.0077 1.5536
0.022367
0.99262
T47D Abemaciclib
CDK4/6
Cell cycle
0.0042816
 -0.0412 0.7664 0.0265 1.3858
0.0037683
0.95899