Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

Data Columns

  • 11 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
cell
Cell reagent
Cell cell
deathAUC
Integral of Increased Fraction Dead under the range of concentrations tested
Death_AUC Numeric 4
gEC50
Small molecule concentration in uM that results in 50% efficacy
GEC50 Text
gR50
Small molecule concentration in uM at which GR(c)=0.5
GR50 Text
gRAOC
Integral of GR(c) over the range of concentrations tested
GR_AOC Numeric 4
gRHillCoefficient
Maximal slope of the dose-response curve
GR Hill Coefficient Numeric 4
gRmax
Normalized growth inhibition rate at the highest tested concentration
GRmax Numeric 4
gRR2
r^2 for the sigmoidal curve fit to the dose-response data
GR r2 Text
pathway Pathway Text
primaryTarget Primary Target Text
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
  • 11 Data Columns