Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9300 0.00230
HCC1806 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9726 -0.00130
Hs 578T Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9359 0.00166
Hs 578T Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.8534 -0.00386
HCC1806 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.9450 -0.00218
Hs 578T Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.5525 0.03059
Hs 578T Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4423 0.04240
BT-549 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9859 0.00538
MCF 10A Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.8001 -0.00568
HCC1806 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.9502 -0.00032
BT-549 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.8348 0.00416
BT-549 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.7689 0.00574
MCF 10A Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0017 0.00024
MCF 10A Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9681 -0.00119
HCC1806 Ipatasertib
0.1
AKT
PI3K/mTOR
 1.0178 -0.00290
HCC1806 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9472 -0.00031
MDA-MB-231 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0315 -0.00166
MDA-MB-231 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9871 -0.00637
MDA-MB-231 Ipatasertib
1.0
AKT
PI3K/mTOR
 1.0136 -0.00088
MDA-MB-231 Ipatasertib
3.1623
AKT
PI3K/mTOR
 1.0049 -0.00480
MCF 10A Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0004 0.00065
MCF7 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9577 0.00290
SK-BR-3 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0397 0.01094
HCC38 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9955 0.00046
HCC38 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0489 0.00810