Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 Abemaciclib
0.001
CDK4/6
Cell cycle
0.9779 0.00362
HCC1806 Abemaciclib
0.0031623
CDK4/6
Cell cycle
0.9667 -0.00301
HCC1806 Abemaciclib
0.01
CDK4/6
Cell cycle
0.9168 0.00484
HCC1806 Abemaciclib
0.031623
CDK4/6
Cell cycle
0.7658 0.01650
HCC1806 Abemaciclib
0.1
CDK4/6
Cell cycle
0.7132 0.01025
HCC1806 Abemaciclib
0.31623
CDK4/6
Cell cycle
0.6567 0.01780
HCC1806 Abemaciclib
1.0
CDK4/6
Cell cycle
0.4501 0.04250
HCC1806 Abemaciclib
3.1623
CDK4/6
Cell cycle
0.1267 0.14911
HCC1806 Abemaciclib
10.0
CDK4/6
Cell cycle
-0.4440 0.69010
HCC1806 Palbociclib
0.00031623
CDK4/6
Cell cycle
1.0473 0.00007
HCC1806 Palbociclib
0.001
CDK4/6
Cell cycle
1.0121 0.00165
HCC1806 Palbociclib
0.0031623
CDK4/6
Cell cycle
0.9535 -0.00157
HCC1806 Palbociclib
0.01
CDK4/6
Cell cycle
0.9497 0.00431
HCC1806 Palbociclib
0.031623
CDK4/6
Cell cycle
0.8470 0.00941
HCC1806 Palbociclib
0.1
CDK4/6
Cell cycle
0.7323 0.02268
HCC1806 Palbociclib
0.31623
CDK4/6
Cell cycle
0.7287 0.01539
HCC1806 Palbociclib
1.0
CDK4/6
Cell cycle
0.6924 0.01844
HCC1806 Palbociclib
3.1623
CDK4/6
Cell cycle
0.7848 0.00614
HCC1806 AZD7762
0.001
CHK1/2
Cell cycle
1.0370 0.00365
HCC1806 AZD7762
0.0031623
CHK1/2
Cell cycle
0.9973 0.00852
HCC1806 AZD7762
0.01
CHK1/2
Cell cycle
0.7268 0.06774
HCC1806 AZD7762
0.031623
CHK1/2
Cell cycle
0.1254 0.31387
HCC1806 AZD7762
0.1
CHK1/2
Cell cycle
-0.2483 0.52952
HCC1806 AZD7762
0.31623
CHK1/2
Cell cycle
-0.2887 0.58594
HCC1806 AZD7762
1.0
CHK1/2
Cell cycle
-0.3313 0.62585
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