Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 Ipatasertib
1.0
AKT
PI3K/mTOR
 1.0055 -0.00454
Hs 578T Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4423 0.04240
Hs 578T Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.5525 0.03059
MDA-MB-231 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.9254 -0.00736
Hs 578T Ipatasertib
0.1
AKT
PI3K/mTOR
 0.7471 0.00023
HCC1806 Ipatasertib
0.1
AKT
PI3K/mTOR
 1.0178 -0.00290
Hs 578T Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.8534 -0.00386
MCF 10A Ipatasertib
10.0
AKT
PI3K/mTOR
 0.6472 -0.00617
MCF7 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9728 0.00441
MCF7 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9327 0.00677
MCF7 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.8212 0.01438
MCF7 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.5403 0.03530
MCF7 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.3934 0.07320
HCC1806 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9999 -0.00551
Hs 578T Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9300 0.00230
MCF 10A Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0017 0.00024
MCF 10A Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0004 0.00065
HCC1806 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9750 0.00451
Hs 578T Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9722 -0.00367
HCC1806 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0171 -0.00556
HCC1806 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9472 -0.00031
HCC1806 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.9450 -0.00218
HCC1806 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9726 -0.00130
SK-BR-3 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9410 0.00816
SK-BR-3 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0397 0.01094