Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1395 ABT-737
0.001
Bcl2/XL
Misc
 1.0994 -0.01093
BT-549 Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.9772 -0.01089
HCC1806 Dinaciclib
0.00031623
pan CDK
Cell cycle
 1.0550 -0.01089
HCC1395 Ceritinib
0.1
ALK
RTK
 1.0650 -0.01086
HCC1954 ABT-737
0.01
Bcl2/XL
Misc
 1.1125 -0.01083
MDA-MB-134-VI Cisplatin
0.0033333
Chemo
Chemotherapy
 0.9932 -0.01078
HCC70 Cisplatin
0.031667
Chemo
Chemotherapy
 1.0748 -0.01076
CAL-120 Torin2
0.0031623
mTOR/ATM/ATR
PI3K/mTOR
 0.8087 -0.01071
PDXHCI002 Ceritinib
0.01
ALK
RTK
 1.0536 -0.01070
HCC1419 Palbociclib
1.0
CDK4/6
Cell cycle
 0.4414 -0.01064
HCC1500 Ipatasertib
3.1623
AKT
PI3K/mTOR
 1.0898 -0.01062
MDA-MB-361 Bleomycin
0.01
Radiation
Misc
 0.9281 -0.01060
HCC1806 Cediranib
0.0031623
VEGFR/cKIT
RTK
 1.0810 -0.01058
MDA-MB-134-VI Dinaciclib
0.00031623
pan CDK
Cell cycle
 1.0543 -0.01056
BT-20 Dinaciclib
0.0031623
pan CDK
Cell cycle
 1.1052 -0.01052
HCC1500 Doxorubicin
0.0031623
Chemo
Chemotherapy
 0.8857 -0.01049
MDA-MB-134-VI Ceritinib
0.001
ALK
RTK
 1.2398 -0.01049
MDA-MB-157 A-1210477
0.31623
Mcl-1
Misc
 1.0039 -0.01046
CAL-85-1 Abemaciclib
0.01
CDK4/6
Cell cycle
 1.0722 -0.01046
BT-20 TGX221
3.1623
PI3Kb
PI3K/mTOR
 1.0471 -0.01046
SK-BR-3 Cediranib
0.31623
VEGFR/cKIT
RTK
 1.0293 -0.01040
MDA-MB-134-VI Luminespib
0.00031623
HSP90
Misc
 1.3361 -0.01039
HCC1954 Olaparib
0.0031623
PARP
Misc
 1.0135 -0.01039
HCC1954 Dinaciclib
0.001
pan CDK
Cell cycle
 1.0713 -0.01038
CAL-51 Luminespib
0.0031623
HSP90
Misc
 0.9154 -0.01036