Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| MCF7 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.7154 | 0.02464 |
| BT-20 | Luminespib | 0.0001 | HSP90 | Misc | 1.0515 | 0.00266 |
| MDA-MB-468 | Torin2 | 0.0001 | mTOR/ATM/ATR | PI3K/mTOR | 1.0038 | 0.00449 |
| SUM1315MO2 | Luminespib | 0.0001 | HSP90 | Misc | 1.0309 | 0.00183 |
| MDA-MB-157 | Volasertib | 0.0001 | PLK | Cell cycle | 1.0247 | -0.00046 |
| HCC1143 | Luminespib | 0.0001 | HSP90 | Misc | 0.9419 | -0.00109 |
| MCF7 | Trametinib | 0.0001 | MEK | MAPK/nRTK | 1.0030 | -0.00089 |
| MDA-MB-157 | Dinaciclib | 0.0001 | pan CDK | Cell cycle | 1.0631 | 0.00045 |
| MCF 10A | Taxol | 0.0001 | Chemo | Chemotherapy | 0.9571 | 0.00191 |
| BT-20 | Torin2 | 0.0001 | mTOR/ATM/ATR | PI3K/mTOR | 1.0519 | 0.00274 |