LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 54.10 | 770.96 | 1546 | 7405 | 0.2088 | 0.2372 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 56.40 | 770.96 | 1576 | 7845 | 0.2008 | 0.2374 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 58.60 | 770.96 | 1566 | 8264 | 0.1895 | 0.2296 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 60.80 | 770.96 | 1578 | 8711 | 0.1811 | 0.2265 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 63.00 | 770.96 | 1598 | 9152 | 0.1746 | 0.2257 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 65.30 | 770.96 | 1595 | 9591 | 0.1663 | 0.2206 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 67.50 | 770.96 | 1617 | 9939 | 0.1626 | 0.2214 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 69.70 | 770.96 | 1608 | 10312 | 0.1559 | 0.2165 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 71.90 | 770.96 | 1595 | 10631 | 0.1500 | 0.2114 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 74.10 | 770.96 | 1590 | 10921 | 0.1456 | 0.2080 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 76.40 | 770.96 | 1589 | 11184 | 0.1421 | 0.2058 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 78.60 | 770.96 | 1584 | 11443 | 0.1384 | 0.2026 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 80.80 | 770.96 | 1616 | 11725 | 0.1378 | 0.2065 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 83.10 | 770.96 | 1589 | 12002 | 0.1324 | 0.1999 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 85.30 | 770.96 | 1606 | 12277 | 0.1309 | 0.2012 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 87.50 | 770.96 | 1618 | 12567 | 0.1288 | 0.2016 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 2.90 | 770.96 | 857 | 886 | 0.9688 | 1.0455 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 5.10 | 770.96 | 956 | 984 | 0.9733 | 0.9974 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 7.30 | 770.96 | 1013 | 1067 | 0.9510 | 0.8479 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 9.60 | 770.96 | 1084 | 1178 | 0.9227 | 0.7828 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 11.90 | 770.96 | 1201 | 1319 | 0.9128 | 0.7941 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.10 | 770.96 | 1301 | 1478 | 0.8812 | 0.7513 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.40 | 770.96 | 1373 | 1625 | 0.8469 | 0.7169 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.60 | 770.96 | 1402 | 1786 | 0.7867 | 0.6422 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 20.80 | 770.96 | 1401 | 1959 | 0.7170 | 0.5614 |