LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.60 | 770.96 | 1716 | 1786 | 0.9602 | 0.9325 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.80 | 770.96 | 1788 | 1959 | 0.9127 | 0.8671 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 23.00 | 770.96 | 1860 | 2193 | 0.8481 | 0.7913 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 25.30 | 770.96 | 1940 | 2456 | 0.7900 | 0.7351 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 27.50 | 770.96 | 2044 | 2754 | 0.7421 | 0.6983 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 29.70 | 770.96 | 2158 | 3022 | 0.7140 | 0.6840 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 31.90 | 770.96 | 2269 | 3294 | 0.6886 | 0.6723 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 34.10 | 770.96 | 2383 | 3605 | 0.6608 | 0.6584 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 36.40 | 770.96 | 2540 | 3985 | 0.6372 | 0.6520 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 38.60 | 770.96 | 2726 | 4421 | 0.6163 | 0.6487 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 40.80 | 770.96 | 2912 | 4874 | 0.5972 | 0.6460 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 43.00 | 770.96 | 3118 | 5280 | 0.5903 | 0.6523 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 45.30 | 770.96 | 3327 | 5677 | 0.5858 | 0.6599 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 47.50 | 770.96 | 3536 | 6082 | 0.5813 | 0.6660 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 49.70 | 770.96 | 3758 | 6511 | 0.5770 | 0.6715 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 51.90 | 770.96 | 3960 | 6944 | 0.5700 | 0.6739 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 54.10 | 770.96 | 4239 | 7405 | 0.5723 | 0.6846 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 56.40 | 770.96 | 4441 | 7845 | 0.5660 | 0.6862 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 58.60 | 770.96 | 4678 | 8264 | 0.5659 | 0.6924 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 60.80 | 770.96 | 4927 | 8711 | 0.5656 | 0.6984 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 63.00 | 770.96 | 5114 | 9152 | 0.5588 | 0.6981 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 65.30 | 770.96 | 5325 | 9591 | 0.5551 | 0.7002 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 67.50 | 770.96 | 5564 | 9939 | 0.5598 | 0.7079 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 69.70 | 770.96 | 5802 | 10312 | 0.5625 | 0.7140 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 71.90 | 770.96 | 6064 | 10631 | 0.5703 | 0.7232 |