LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)

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Cell Small Molecule Small Mol Concentration (uM) Time Point (hr) Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value Assay Plate Assay Well
MCF 10A-H2B-mCherry Trametinib
0.0016667
6.94 771.67 1045 1045 0.9999 0.9995
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
18.22 771.67 1714 1741 0.9843 0.9732
MN20160304_L01
C03
MCF 10A-H2B-mCherry Neratinib
0.056234
12.28 770.25 1277 1358 0.9403 0.8550
MN20160304_L02
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
16.00 771.67 1595 1585 1.0060 1.0115
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
13.78 771.67 1440 1459 0.9865 0.9706
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
2.49 771.67 869 867 1.0014 1.0171
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
22.66 771.67 1889 2141 0.8821 0.8367
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
27.11 771.67 2131 2675 0.7966 0.7618
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
29.33 771.67 2368 2939 0.8056 0.7880
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
36.00 771.67 2852 3884 0.7342 0.7518
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
38.22 771.67 2995 4299 0.6966 0.7285
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
42.67 771.67 3462 5155 0.6715 0.7295
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
44.89 771.67 3751 5541 0.6769 0.7436
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
53.77 771.67 4682 7256 0.6452 0.7465
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
55.99 771.67 4853 7690 0.6311 0.7408
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
60.44 771.67 5307 8530 0.6221 0.7441
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
62.66 771.67 5519 8978 0.6147 0.7432
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
69.32 771.67 5955 10212 0.5831 0.7305
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
71.54 771.67 5982 10532 0.5679 0.7214
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
76.02 771.67 6115 11106 0.5506 0.7126
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
78.25 771.67 5962 11367 0.5245 0.6936
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
4.71 771.67 956 956 0.9996 0.9975
MN20160304_L01
C03
MCF 10A-H2B-mCherry Trametinib
0.0016667
11.56 771.67 1265 1280 0.9878 0.9667
MN20160304_L01
C03
MCF 10A-H2B-mCherry Neratinib
0.056234
25.62 770.25 1615 2514 0.6422 0.5430
MN20160304_L02
C03
MCF 10A-H2B-mCherry Neratinib
0.056234
23.39 770.25 1605 2244 0.7151 0.6093
MN20160304_L02
C03