LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 2.49 | 771.67 | 970 | 867 | 1.1178 | 2.8617 | MN20160304_L01 | I15 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 2.49 | 771.67 | 835 | 867 | 0.9623 | 0.5935 | MN20160304_L01 | D14 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 2.49 | 771.67 | 749 | 867 | 0.8632 | -0.1615 | MN20160304_L01 | E11 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 2.49 | 771.67 | 811 | 867 | 0.9346 | 0.3413 | MN20160304_L01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 2.49 | 771.67 | 987 | 867 | 1.1374 | 3.2791 | MN20160304_L01 | K06 |
| MCF 10A-H2B-mCherry | 0 | 2.49 | 771.67 | 823 | 867 | 0.9484 | 0.4629 | MN20160304_L01 | F17 | |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 2.49 | 771.67 | 937 | 867 | 1.0798 | 2.1477 | MN20160304_L01 | K19 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 2.49 | 771.67 | 938 | 867 | 1.0810 | 2.1676 | MN20160304_L01 | N06 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 2.49 | 771.67 | 869 | 867 | 1.0014 | 1.0171 | MN20160304_L01 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 2.49 | 771.67 | 975 | 867 | 1.1236 | 2.9808 | MN20160304_L01 | N20 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 2.49 | 771.67 | 1018 | 867 | 1.1731 | 4.1367 | MN20160304_L01 | J13 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 2.49 | 771.67 | 775 | 867 | 0.8931 | 0.0258 | MN20160304_L01 | D10 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 2.49 | 771.67 | 824 | 867 | 0.9496 | 0.4734 | MN20160304_L01 | M06 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 2.49 | 771.67 | 795 | 867 | 0.9162 | 0.1924 | MN20160304_L01 | N16 |
| MCF 10A-H2B-mCherry | 0 | 2.49 | 771.67 | 952 | 867 | 1.0971 | 2.4572 | MN20160304_L01 | K09 | |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 2.49 | 771.67 | 716 | 867 | 0.8251 | -0.3574 | MN20160304_L01 | F03 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 2.49 | 771.67 | 978 | 867 | 1.1271 | 3.0537 | MN20160304_L01 | J09 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 2.49 | 771.67 | 817 | 867 | 0.9415 | 0.4010 | MN20160304_L01 | I03 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 2.49 | 771.67 | 989 | 867 | 1.1397 | 3.3305 | MN20160304_L01 | J17 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 2.49 | 771.67 | 883 | 867 | 1.0176 | 1.2168 | MN20160304_L01 | L21 |