Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) - Dataset (ID:20276)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Number of Cells Primary Antibody (488) Secondary Antibody (488) Protein Detected (488) Mean Fluorescence Intensity (488) Primary Antibody (647) Secondary Antibody (647) Protein Detected (647) Mean Fluorescence Intensity (647) Plate Name Plate Well
A-375 Vemurafenib Anacardic acid 1.0000 0.1067
uM
 48
hr
 1 1913 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 163.69 NGFR rabbit IgG(H+L) / donkey NGFR 176.01
A375-B2-rep1
G3
COLO 858 Vemurafenib Rocilinostat 0.3160 2.6667
uM
 48
hr
 1 755 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 163.81 NGFR rabbit IgG(H+L) / donkey NGFR 184.22
Colo858-A2-rep1
B5
A-375 Vemurafenib 1.0000
uM
 48
hr
 1 2285 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 163.90 NGFR rabbit IgG(H+L) / donkey NGFR 189.57
A375-B2-rep1
A8
WM-115 Vemurafenib 1.0000
uM
 48
hr
 2 1297 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 163.96 NGFR rabbit IgG(H+L) / donkey NGFR 1130.50
WM115-B1-rep2
A7
COLO 858 Vemurafenib I-BET 0.3160 0.5333
uM
 48
hr
 1 2681 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 164.14 NGFR rabbit IgG(H+L) / donkey NGFR 33.28
Colo858-B1-rep1
E7
A-375 Vemurafenib 1.0000
uM
 48
hr
 1 1702 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 164.33 NGFR rabbit IgG(H+L) / donkey NGFR 152.80
A375-B2-rep1
H10
A-375 Vemurafenib 1.0000
uM
 48
hr
 2 1793 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 164.73 NGFR rabbit IgG(H+L) / donkey NGFR 197.31
A375-A2-rep2
A11
A-375 Vemurafenib 1.0000
uM
 48
hr
 2 1514 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 164.99 NGFR rabbit IgG(H+L) / donkey NGFR 137.41
A375-B2-rep2
H9
A-375 Vemurafenib Olaparib 1.0000 2.6667
uM
 48
hr
 1 1874 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 164.99 NGFR rabbit IgG(H+L) / donkey NGFR 198.38
A375-A2-rep1
B2
A-375 Vemurafenib Tranylcypromine 1.0000 0.1067
uM
 48
hr
 1 2043 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 164.99 NGFR rabbit IgG(H+L) / donkey NGFR 192.09
A375-B2-rep1
G6
A-375 Vemurafenib I-BET151 1.0000 0.1067
uM
 48
hr
 1 2693 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 165.02 NGFR rabbit IgG(H+L) / donkey NGFR 202.21
A375-B2-rep1
F7
COLO 858 Vemurafenib Mocetinostat 0.3160 2.6667
uM
 48
hr
 2 2331 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 165.13 NGFR rabbit IgG(H+L) / donkey NGFR 22.79
Colo858-A2-rep2
E4
A-375 Vemurafenib (+)-JQ1 1.0000 2.6667
uM
 48
hr
 2 2251 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 165.40 NGFR rabbit IgG(H+L) / donkey NGFR 86.81
A375-A2-rep2
C7
A-375 Vemurafenib 1.0000
uM
 48
hr
 1 1834 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 165.77 NGFR rabbit IgG(H+L) / donkey NGFR 166.59
A375-A2-rep1
A10
A-375 Vemurafenib 1.0000
uM
 48
hr
 2 2082 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 165.98 NGFR rabbit IgG(H+L) / donkey NGFR 171.03
A375-B2-rep2
A9
A-375 Vemurafenib 1.0000
uM
 48
hr
 1 1748 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.30 NGFR rabbit IgG(H+L) / donkey NGFR 148.34
A375-B2-rep1
H4
A-375 Vemurafenib Resveratrol 1.0000 0.5333
uM
 48
hr
 1 2611 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.44 NGFR rabbit IgG(H+L) / donkey NGFR 163.00
A375-B1-rep1
E5
A-375 Vemurafenib UNC669 1.0000 0.1067
uM
 48
hr
 1 2260 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.44 NGFR rabbit IgG(H+L) / donkey NGFR 151.61
A375-B2-rep1
B8
A-375 Vemurafenib C646 1.0000 0.1067
uM
 48
hr
 2 2676 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.48 NGFR rabbit IgG(H+L) / donkey NGFR 161.93
A375-B2-rep2
E3
A-375 Vemurafenib Tranylcypromine 1.0000 0.5333
uM
 48
hr
 2 1765 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.51 NGFR rabbit IgG(H+L) / donkey NGFR 168.79
A375-B1-rep2
G6
A-375 Vemurafenib UNC1215 1.0000 0.5333
uM
 48
hr
 2 2762 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.53 NGFR rabbit IgG(H+L) / donkey NGFR 192.69
A375-B1-rep2
C8
COLO 858 Vemurafenib Pracinostat 0.3160 0.5333
uM
 48
hr
 2 326 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.82 NGFR rabbit IgG(H+L) / donkey NGFR 26.66
Colo858-B1-rep2
F4
A-375 Vemurafenib Garcinol 1.0000 0.5333
uM
 48
hr
 1 2101 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 167.05 NGFR rabbit IgG(H+L) / donkey NGFR 180.94
A375-B1-rep1
F3
A-375 Vemurafenib UNC0638 1.0000 0.1067
uM
 48
hr
 2 2188 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 167.32 NGFR rabbit IgG(H+L) / donkey NGFR 140.34
A375-B2-rep2
G5
A-375 Vemurafenib (-)-JQ1 1.0000 2.6667
uM
 48
hr
 2 3409 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 167.33 NGFR rabbit IgG(H+L) / donkey NGFR 293.21
A375-A2-rep2
D7