Olaparib - Small Molecule (ID:10144-101)

HMS LINCS ID: 10144-101
Name: Olaparib
Alternative Names: AZD2281; KU-0059436
LINCS ID: LSM-1145
PubChem CID: 23725625
ChEBI ID:
ChEMBL ID:
Molecular Mass: 434.18
InChi: InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)
InChi Key: FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Relevant Citations:
Date Publicly Available:
Most Recent Update: 2016-04-04

Nominal Targets:

Small Molecule Protein Effective Concentration Key References
Olaparib PARP-1
5 nM
J Med Chem. 2008 Oct 23;51(20):6581-91. PMID: 18800822

Batch Information for HMSL10144-101-2:

HMS LINCS Batch ID: 10144-101-2
Provider: Haoyuan chemexpress
Provider Catalog ID: HY-10162
Provider Batch ID: HM-042_8-20110726
Salt: 101
Molecular Formula: C24H23FN4O3
Molecular Weight: 434.46
Purity:
Purification Method:
Chemical Synthesis Reference:
Date Publicly Available: 2013-05-08
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10144-101-2:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10144-101-2_LCMS.pdf