Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10051-3 | Lapatinib | GW-572016; Tykerb | LSM-1051 |  | 208908 |
| 10008-3 | Sorafenib | BAY-439006 | LSM-1008 |  | 216239 |
| 10261-1 | Ixabepilone | Azaepothilone B; Ixempra | LSM-43293 |  | 216344 |
| 10146-2 | Omipalisib | GSK2126458; GSK2126458A | LSM-1147 |  | 25167777 |
| 10255-1 | GSK1838705A | LSM-4276 |  | 25182616 | |
| 10506-1 | Dichloroacetate |  | 25975 | ||
| 10175-3 | Sunitinib | Sutent; SU11248 | LSM-42800 |  | 3086686 |
| 10507-1 | Disulfiram | Tetraethylthiuram disulfide; TETD |  | 3117 | |
| 10248-1 | Doxorubicin | Adriamycin | LSM-4062 |  | 31703 |
| 10238-1 | 5-FU | Fluorouracil | LSM-4261 |  | 3385 |
| 10346-1 | Valproic acid | Depakine | LSM-4620 |  | 3549980 |
| 10250-1 | Etoposide | LSM-6348 |  | 36462 | |
| 10516-1 | Ribavirin | Tribavirin |  | 37542 | |
| 10266-1 | NSC 663284 | LSM-2042 |  | 379077 | |
| 10241 | Bortezomib | Velcade | LSM-6281 |  | 387447 |
| 10241-1 | Bortezomib | Velcade | LSM-6281 | | 387447 |
| 10241-4 | Bortezomib | Velcade | LSM-6281 | | 387447 |
| 10511-1 | Mebendazole | Vermox |  | 4030 | |
| 10249-1 | Epirubicin | Ellence | LSM-2078 |  | 41867 |
| 10102-3 | Taxol | Paclitaxel | LSM-1102 |  | 441276 |
| 10272-1 | Pemetrexed | Alimta | LSM-6353 |  | 446556 |
| 10258-1 | Ibandronate | Boniva | LSM-4279 |  | 44828485 |
| 10273-1 | Purvalanol A | LSM-3118 |  | 456214 | |
| 10267-1 | NU6102 | LSM-4287 |  | 4566 | |
| 10270-1 | Oxamflatin | LSM-4290 |  | 4611 |