Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10208-2 | JNK-IN-5A | TCS JNK 5a; KIN001-188 | LSM-1209 |  | 766949 |
| 10223-2 | AG1478 | Tyrphostin | LSM-1224 |  | 2051 |
| 10230-2 | Lestaurtinib | CEP-701 | LSM-1231 |  | 126565 |
| 10266-1 | NSC 663284 | LSM-2042 |  | 379077 | |
| 10249-1 | Epirubicin | Ellence | LSM-2078 |  | 41867 |
| 10246-1 | CPT-11 | Irinotecan | LSM-2167 |  | 60838 |
| 10228-2 | IKK16 | LSM-2309 |  | 9549298 | |
| 10273-1 | Purvalanol A | LSM-3118 |  | 456214 | |
| 10271-2 | PD 98059 | LSM-3394 |  | 4713 | |
| 10280-1 | Triciribine | LSM-3810 |  | 65399 | |
| 10282-1 | Vorinostat | suberoylanilide hydroxamic acid (SAHA); Zolinza | LSM-3828 |  | 5311 |
| 10248-1 | Doxorubicin | Adriamycin | LSM-4062 |  | 31703 |
| 10232-2 | Dactolisib | BEZ235; NVP-BEZ235 | LSM-4255 |  | 11977753 |
| 10235-2 | Everolimus | RAD001 | LSM-4258 |  | 53398658 |
| 10238-1 | 5-FU | Fluorouracil | LSM-4261 |  | 3385 |
| 10239-1 | AG1024 | Tyrphostin AG 1024 | LSM-4262 |  | 2044 |
| 10240-1 | AS-252424 | LSM-4263 |  | 56965900 | |
| 10243-1 | CGC-11047 | PG11047 | LSM-4266 |  | 476863 |
| 10245-1 | Cisplatin | CDDP; cis-Diaminodichloroplatinum; Cisplatinum; Lederplatin; Briplatin; Cismaplat | LSM-4268 |  | |
| 10251-1 | Fascaplysin | LSM-4272 |  | 73293 | |
| 10253-1 | Glycyl-H-1152 | LSM-4274 |  | ||
| 10255-1 | GSK1838705A | LSM-4276 |  | 25182616 | |
| 10257-1 | GSK923295 | LSM-4278 |  | 68651179 | |
| 10108-2 | Geldanamycin | LSM-42789 |  | 644250 | |
| 10258-1 | Ibandronate | Boniva | LSM-4279 |  | 44828485 |