Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)

Small Molecules Studied

HMS LINCS ID Name Alternative Names LINCS ID Structure Image PubChem CID
10263-1 LBH589
Panobinostat
LSM-4284 57519507
10345-3 Torkinib
PP242
LSM-6357 57347681
10240-1 AS-252424 LSM-4263 56965900
10021-5 Tozasertib
VX680; MK-0457
LSM-1021 5494449
10275-1 (Z)-4-Hydroxytamoxifen LSM-43294 53770298
10235-2 Everolimus
RAD001
LSM-4258 53398658
10189-2 Bosutinib
SKI-606
LSM-1190 5328940
10281-1 Vinorelbine
Navelbine
LSM-6302 5311497
10282-1 Vorinostat
suberoylanilide hydroxamic acid (SAHA); Zolinza
LSM-3828 5311
10269-1 Oxaliplatin
Eloxatin
LSM-44941 5310940
10023-3 Imatinib
Gleevec; Glivec; CGP-57148B; STI-571
LSM-1023 5291
10343-1 Baicalein LSM-6355 5281605
10242-1 Carboplatin LSM-44959 5237030
10052-3 Sirolimus
Rapamycin
LSM-1052 5040
10243-1 CGC-11047
PG11047
LSM-4266 476863
10271-2 PD 98059 LSM-3394 4713
10062-3 GSK1070916
KIN001-216
LSM-1062 46885626
10107-2 MG-132 LSM-1107 462382
10107 MG-132 LSM-1107 462382
10107-5 MG-132 LSM-1107 462382
10270-1 Oxamflatin LSM-4290 4611
10267-1 NU6102 LSM-4287 4566
10273-1 Purvalanol A LSM-3118 456214
10258-1 Ibandronate
Boniva
LSM-4279 44828485
10272-1 Pemetrexed
Alimta
LSM-6353 446556