Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10506-1 | Dichloroacetate |  | 25975 | ||
| 10513-1 | Nelfinavir | Viracept |  | 64143 | |
| 10516-1 | Ribavirin | Tribavirin |  | 37542 | |
| 10514-1 | PS-1145 |  | 9949093 | ||
| 10507-1 | Disulfiram | Tetraethylthiuram disulfide; TETD |  | 3117 | |
| 10511-1 | Mebendazole | Vermox |  | 4030 | |
| 10508-1 | FTase Inhibitor I | B581 |  | 132887 | |
| 10520-1 | TCS PIM-1 1 |  | 1235170 | ||
| 10276-1 | TCS 2312 | LSM-6362 |  | 11258443 | |
| 10247-1 | Docetaxel | Taxotere | LSM-6360 |  | 148124 |
| 10237-1 | 5-DFUR | 5-FdUR; Doxifluridine | LSM-6359 |  | 18343 |
| 10348-1 | Z-Leu-Leu-Norvalinal | MG-115 | LSM-6358 |  | 9868928 |
| 10345-3 | Torkinib | PP242 | LSM-6357 |  | 57347681 |
| 10344-1 | Olomoucine II | LSM-6356 |  | 10067756 | |
| 10343-1 | Baicalein | LSM-6355 |  | 5281605 | |
| 10272-1 | Pemetrexed | Alimta | LSM-6353 |  | 446556 |
| 10268-1 | Nutlin 3a | LSM-6351 |  | 11433190 | |
| 10250-1 | Etoposide | LSM-6348 |  | 36462 | |
| 10281-1 | Vinorelbine | Navelbine | LSM-6302 |  | 5311497 |
| 10241 | Bortezomib | Velcade | LSM-6281 |  | 387447 |
| 10241-4 | Bortezomib | Velcade | LSM-6281 | | 387447 |
| 10241-1 | Bortezomib | Velcade | LSM-6281 | | 387447 |
| 10265-1 | Pevonedistat | MLN 4924; MLN-4924; MLN4924 | LSM-6263 |  | 16720766 |
| 10260-1 | Ispinesib | SB-715992 | LSM-5732 |  | 6851740 |
| 10264-1 | Methotrexate | Rheumatrex; Trexall; Amethopterin; MTX | LSM-5690 |  | 126941 |