Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10098-2 | Gefitinib | ZD1839; Iressa | LSM-1098 |  | 123631 |
| 10021-5 | Tozasertib | VX680; MK-0457 | LSM-1021 |  | 5494449 |
| 10513-1 | Nelfinavir | Viracept |  | 64143 | |
| 10511-1 | Mebendazole | Vermox |  | 4030 | |
| 10241-1 | Bortezomib | Velcade | LSM-6281 |  | 387447 |
| 10241 | Bortezomib | Velcade | LSM-6281 | | 387447 |
| 10241-4 | Bortezomib | Velcade | LSM-6281 | | 387447 |
| 10239-1 | AG1024 | Tyrphostin AG 1024 | LSM-4262 |  | 2044 |
| 10223-2 | AG1478 | Tyrphostin | LSM-1224 |  | 2051 |
| 10516-1 | Ribavirin | Tribavirin |  | 37542 | |
| 10507-1 | Disulfiram | Tetraethylthiuram disulfide; TETD |  | 3117 | |
| 10208-2 | JNK-IN-5A | TCS JNK 5a; KIN001-188 | LSM-1209 |  | 766949 |
| 10247-1 | Docetaxel | Taxotere | LSM-6360 |  | 148124 |
| 10236-1 | 17-AAG | Tanespimycin | LSM-43239 |  | 151069 |
| 10175-3 | Sunitinib | Sutent; SU11248 | LSM-42800 |  | 3086686 |
| 10282-1 | Vorinostat | suberoylanilide hydroxamic acid (SAHA); Zolinza | LSM-3828 |  | 5311 |
| 10189-2 | Bosutinib | SKI-606 | LSM-1190 |  | 5328940 |
| 10260-1 | Ispinesib | SB-715992 | LSM-5732 |  | 6851740 |
| 10264-1 | Methotrexate | Rheumatrex; Trexall; Amethopterin; MTX | LSM-5690 |  | 126941 |
| 10052-3 | Sirolimus | Rapamycin | LSM-1052 |  | 5040 |
| 10235-2 | Everolimus | RAD001 | LSM-4258 |  | 53398658 |
| 10345-3 | Torkinib | PP242 | LSM-6357 |  | 57347681 |
| 10243-1 | CGC-11047 | PG11047 | LSM-4266 |  | 476863 |
| 10263-1 | LBH589 | Panobinostat | LSM-4284 |  | 57519507 |
| 10102-3 | Taxol | Paclitaxel | LSM-1102 |  | 441276 |