Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7907.018 | 0.9599 | 0.9469 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7907.018 | 0.9953 | 0.9939 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7907.018 | 1.0328 | 1.0428 | 1.5217 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9759.006 | 0.9744 | 0.9596 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7912.018 | 1.0557 | 1.1562 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7912.018 | 0.8958 | 0.7166 | 0.7203 | |
| SUM102PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9777.124 | 1.0847 | 1.2765 | 0.6278 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7912.018 | 0.9591 | 0.8874 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7912.018 | 0.7818 | 0.4212 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7912.018 | 0.8690 | 0.6458 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7912.018 | 1.0116 | 1.0323 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9759.006 | 0.9764 | 0.9628 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9759.006 | 1.0209 | 1.0327 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9759.006 | 1.0802 | 1.1251 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9759.006 | 1.0193 | 1.0304 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9759.006 | 1.0499 | 1.0780 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9759.006 | 1.0195 | 1.0306 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9759.006 | 0.4473 | 0.0623 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9759.006 | 1.0411 | 1.0644 | 1.2714 | |
| SUM102PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9777.124 | 0.9766 | 0.9260 | 0.6278 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9760.026 | 1.0342 | 1.0637 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9760.026 | 0.9711 | 0.9461 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9760.026 | 1.0304 | 1.0567 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9760.026 | 1.0241 | 1.0449 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9760.026 | 1.0628 | 1.1169 | 1.0724 |