Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 92.7 | uM | 7810.006 | 0.5600 | 0.1021 | 0.9730 | |
SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9759.006 | 0.0609 | -0.7787 | 1.2714 | |
600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9118.006 | 0.0070 | -0.9773 | 1.1089 | |
SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9797.006 | 0.0023 | -1.0000 | 0.4196 | |
LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9536.006 | 0.0144 | -0.9317 | 1.2564 | |
SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9830.006 | 0.0060 | -0.8987 | 1.7160 | |
MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9708.006 | 0.0004 | -1.0000 | 0.6313 |