Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF - Dataset (ID:20265)
Proteins Studied
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| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 201350 | FOXO3a | 201350 | O43524 | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 | |||||
| 201357 | EGF | 201357 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech | ||||
| 201297 | Rb (pS807; pS811) | 201297 | P06400 | pS807; pS811 | |||||
| 201386 | CDK1 (pY15) | 201386 | P06493 | pY15 | |||||
| 201384 | Cyclin-B1 | 201384 | P14635 | G2/mitotic-specific cyclin-B1 | |||||
| 201364 | Cyclin-A2 | 201364 | P20248 | Cyclin-A | |||||
| 201351 | Cyclin-D1 | 201351 | P24385 | G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene | |||||
| 201361 | Cyclin-E1 | 201361 | P24864 | G1/S-specific cyclin-E1 | |||||
| 201366 | CDK2 (pT160) | 201366 | P24941 | pT160 | |||||
| 201387 | CDK2 (pY15) | 201387 | P24941 | pY15 | |||||
| 201303 | ERK-1 (pT202; pY204) | 201303 | P27361 | pT202; pY204 | |||||
| 201337 | ERK-1 (pT202) | 201337 | P27361 | pT202 | |||||
| 201304 | ERK-2 (pT185; pY187) | 201304 | P28482 | pT185; pY187 | |||||
| 201338 | ERK-2 (pT185) | 201338 | P28482 | pT185 | |||||
| 201359 | Cyclin-D2 | 201359 | P30279 | G1/S-specific cyclin-D2 | |||||
| 201360 | Cyclin-D3 | 201360 | P30281 | G1/S-specific cyclin-D3 | |||||
| 201380 | WEE1hu (pS642) | 201380 | P30291 | pS642 | |||||
| 201358 | Cdc25A | 201358 | P30304 | M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A | |||||
| 201139 | Cdc25C | 201139 | P30307 | M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C | |||||
| 201295 | p21 | 201295 | P38936 | Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6 | |||||
| 201369 | mTOR (pS2448) | 201369 | P42345 | pS2448 | |||||
| 201344 | p27Kip1 | 201344 | P46527 | Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27 | |||||
| 201388 | p27Kip1 (pS10) | 201388 | P46527 | pS10 | |||||
| 201379 | Tuberin (pS1387) | 201379 | P49815 | pS1387 | |||||
| 201367 | GSK-3 alpha (pS21) | 201367 | P49840 | pS21 |