PF-3758309 KiNativ -- single dose experiment - Dataset (ID:20254)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| PF-3758309 | THP-1 | PRPK | FLSGLELVKQGAEAR | ATP Loop | 12.4 | 1 | uM |
| PF-3758309 | THP-1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | 63.9 | 1 | uM |
| PF-3758309 | THP-1 | SIK3 | VAIKIIDKTQLDEENLKK | Lys1 | 25.0 | 1 | uM |
| PF-3758309 | THP-1 | RIPK3 | DLKPSNVLLDPELHVK | Lys2 | -14.0 | 1 | uM |
| PF-3758309 | THP-1 | RSK1,RSK2,RSK3_domain1 | DLKPENILLDEEGHIK | Lys2 | 90.6 | 1 | uM |
| PF-3758309 | THP-1 | RSK1 (Domain 2) | ATNMEYAVKVIDK | Lys1 | -23.7 | 1 | uM |
| PF-3758309 | THP-1 | RSK2_domain2 | DLKPSNILYVDESGNPESIR | Lys2 | -6.9 | 1 | uM |
| PF-3758309 | THP-1 | SGK3 | FYAVKVLQK | Lys1 | -16.1 | 1 | uM |
| PF-3758309 | THP-1 | SLK | DLKAGNILFTLDGDIK | Lys2 | 17.6 | 1 | uM |
| PF-3758309 | THP-1 | SNRK | DLKPENVVFFEK | Lys2 | -7.9 | 1 | uM |
| PF-3758309 | THP-1 | SRPK1/2 | FVAMKVVK | Lys1 | 89.2 | 1 | uM |
| PF-3758309 | THP-1 | STLK6 | HTPTGTLVTIKITNLENCNEER | Lys1 | -12.8 | 1 | uM |
| PF-3758309 | THP-1 | SYK | TVAVKILK | Lys1 | 6.7 | 1 | uM |
| PF-3758309 | THP-1 | TLK2 | YVAVKIHQLNK | Lys1 | 64.3 | 1 | uM |
| PF-3758309 | THP-1 | ULK1 | DLKPQNILLSNPAGR | Lys2 | -9.5 | 1 | uM |
| PF-3758309 | THP-1 | ULK3 | EVVAIKCVAK | Lys1 | 41.4 | 1 | uM |
| PF-3758309 | THP-1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | 0.9 | 1 | uM |
| PF-3758309 | THP-1 | Wnk1,Wnk2,Wnk4 | IGDLGLATLKR | Activation Loop | -3.8 | 1 | uM |
| PF-3758309 | THP-1 | MLTK | WISQDKEVAVKK | Lys1 | -6.3 | 1 | uM |
| PF-3758309 | THP-1 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | 8.4 | 1 | uM |
| PF-3758309 | THP-1 | M4K3 | NVNTGELAAIKVIK | Lys1 | 28.7 | 1 | uM |
| PF-3758309 | THP-1 | MARK3 | EVAIKIIDKTQLNPTSLQK | Lys1 | 89.4 | 1 | uM |
| PF-3758309 | THP-1 | PIP4K2A | AKELPTLKDNDFINEGQK | ATP | 4.1 | 1 | uM |
| PF-3758309 | THP-1 | MAP3K5,MAP3K6,MAP3K7 | IAIKEIPERDSR | Lys1 | -3.8 | 1 | uM |