LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | CGP60474 | 0.12 | uM | LJP6 | 1 | G05 | 72 | hr | 1097 | 656 | 3610 | 0.1817 | -0.2587 |
| BT-20 | Sirolimus | 0.12 | uM | LJP6 | 1 | L17 | 72 | hr | 1097 | 2057 | 3610 | 0.5697 | 0.4416 |
| BT-20 | SNS-032 | 0.37 | uM | LJP6 | 1 | H16 | 72 | hr | 1097 | 641 | 3610 | 0.1775 | -0.2686 |
| BT-20 | CGP60474 | 0.37 | uM | LJP6 | 1 | G04 | 72 | hr | 1097 | 658 | 3610 | 0.1822 | -0.2574 |
| BT-20 | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 1097 | 3009 | 3610 | 0.8334 | 0.7987 |
| BT-20 | AZD7762 | 0.37 | uM | LJP6 | 1 | L04 | 72 | hr | 1097 | 2004 | 3610 | 0.5550 | 0.4198 |
| BT-20 | A443654 | 0.12 | uM | LJP6 | 1 | I23 | 72 | hr | 1097 | 1697 | 3610 | 0.4700 | 0.2889 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1097 | 547 | 3610 | 0.1515 | -0.3331 |
| BT-20 | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 1097 | 1761 | 3610 | 0.4877 | 0.3169 |
| BT-20 | KIN001-043 | 0.12 | uM | LJP6 | 1 | C11 | 72 | hr | 1097 | 3688 | 3610 | 1.0214 | 1.0248 |
| BT-20 | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 1097 | 710 | 3610 | 0.1966 | -0.2238 |
| BT-20 | ZSTK474 | 0.37 | uM | LJP6 | 1 | M16 | 72 | hr | 1097 | 2009 | 3610 | 0.5564 | 0.4219 |
| BT-20 | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 1097 | 522 | 3610 | 0.1446 | -0.3510 |
| BT-20 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1097 | 578 | 3610 | 0.1601 | -0.3114 |
| BT-20 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1097 | 445 | 3610 | 0.1233 | -0.4086 |
| BT-20 | KIN001-043 | 3.33 | uM | LJP6 | 1 | C08 | 72 | hr | 1097 | 3430 | 3610 | 0.9500 | 0.9412 |
| BT-20 | AZD7762 | 0.04 | uM | LJP6 | 1 | L06 | 72 | hr | 1097 | 3505 | 3610 | 0.9708 | 0.9658 |
| BT-20 | Selumetinib | 0.37 | uM | LJP6 | 1 | M10 | 72 | hr | 1097 | 3682 | 3610 | 1.0198 | 1.0229 |
| BT-20 | AZD7762 | 0.12 | uM | LJP6 | 1 | L05 | 72 | hr | 1097 | 2554 | 3610 | 0.7074 | 0.6350 |
| BT-20 | KIN001-043 | 1.11 | uM | LJP6 | 1 | C09 | 72 | hr | 1097 | 3641 | 3610 | 1.0084 | 1.0098 |
| BT-20 | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 1097 | 1334 | 3610 | 0.3695 | 0.1204 |
| BT-20 | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 1097 | 714 | 3610 | 0.1978 | -0.2213 |
| BT-20 | AZD8055 | 0.37 | uM | LJP6 | 1 | A10 | 72 | hr | 1097 | 1109 | 3610 | 0.3072 | 0.0062 |
| BT-20 | Afatinib | 3.33 | uM | LJP6 | 1 | G20 | 72 | hr | 1097 | 3204 | 3610 | 0.8874 | 0.8657 |
| BT-20 | Afatinib | 1.11 | uM | LJP6 | 1 | G21 | 72 | hr | 1097 | 3040 | 3610 | 0.8420 | 0.8095 |