LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WYE-125132 | 0.12 | uM | LJP6 | 1 | L11 | 72 | hr | 1209 | 1197 | 3823 | 0.3131 | -0.0063 |
| MCF7 | Dasatinib | 0.04 | uM | LJP6 | 1 | I06 | 72 | hr | 1209 | 1597 | 3823 | 0.4177 | 0.1822 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 1 | A18 | 72 | hr | 1209 | 702 | 3823 | 0.1836 | -0.2794 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 1 | A22 | 72 | hr | 1209 | 2806 | 3980 | 0.7050 | 0.6319 |
| MCF7 | Dasatinib | 0.04 | uM | LJP5 | 1 | D06 | 72 | hr | 1209 | 2912 | 3980 | 0.7317 | 0.6675 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 1209 | 1059 | 3823 | 0.2770 | -0.0769 |
| MCF7 | Dasatinib | 3.33 | uM | LJP5 | 1 | D02 | 72 | hr | 1209 | 1648 | 3980 | 0.4141 | 0.1972 |
| MCF7 | Dasatinib | 0.12 | uM | LJP6 | 1 | I05 | 72 | hr | 1209 | 1357 | 3823 | 0.3550 | 0.0717 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 1 | A17 | 72 | hr | 1209 | 586 | 3823 | 0.1533 | -0.3537 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 1 | A19 | 72 | hr | 1209 | 924 | 3980 | 0.2322 | -0.1451 |
| MCF7 | Dasatinib | 0.12 | uM | LJP5 | 1 | D05 | 72 | hr | 1209 | 2313 | 3980 | 0.5812 | 0.4583 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1209 | 1119 | 3980 | 0.2812 | -0.0443 |
| MCF7 | Dasatinib | 10 | uM | LJP6 | 1 | I01 | 72 | hr | 1209 | 1194 | 3823 | 0.3123 | -0.0078 |
| MCF7 | Dasatinib | 0.37 | uM | LJP6 | 1 | I04 | 72 | hr | 1209 | 1723 | 3823 | 0.4507 | 0.2375 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 1209 | 595 | 3823 | 0.1556 | -0.3478 |
| MCF7 | BMS345541 | 10 | uM | LJP6 | 1 | D01 | 72 | hr | 1209 | 462 | 3823 | 0.1209 | -0.4399 |
| MCF7 | Dasatinib | 0.37 | uM | LJP5 | 1 | D04 | 72 | hr | 1209 | 1693 | 3980 | 0.4254 | 0.2161 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 1209 | 957 | 3823 | 0.2503 | -0.1316 |
| MCF7 | KIN001-043 | 0.37 | uM | LJP6 | 1 | C10 | 72 | hr | 1209 | 3329 | 3823 | 0.8708 | 0.8401 |
| MCF7 | Dasatinib | 1.11 | uM | LJP6 | 1 | I03 | 72 | hr | 1209 | 1622 | 3823 | 0.4243 | 0.1933 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1209 | 672 | 3823 | 0.1758 | -0.2981 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 1 | B17 | 72 | hr | 1209 | 1346 | 3980 | 0.3382 | 0.0642 |
| MCF7 | Dasatinib | 1.11 | uM | LJP5 | 1 | D03 | 72 | hr | 1209 | 1390 | 3980 | 0.3492 | 0.0843 |
| MCF7 | Barasertib | 3.33 | uM | LJP5 | 1 | D08 | 72 | hr | 1209 | 1451 | 3980 | 0.3646 | 0.1117 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 1 | D09 | 72 | hr | 1209 | 1462 | 3980 | 0.3673 | 0.1166 |