LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 CP724714
10
uM
LJP5
3
A07
72
hr
1209 2961 4376 0.6766 0.6203
MCF7 BX-912
1.11
uM
LJP5
3
L21
72
hr
1209 2132 4376 0.4872 0.3573
MCF7 BX-912
3.33
uM
LJP5
2
L20
72
hr
1209 1885 4252 0.4432 0.2771
MCF7 BX-912
3.33
uM
LJP5
3
L20
72
hr
1209 1687 4376 0.3855 0.1964
MCF7 Dasatinib
0.04
uM
LJP5
1
D06
72
hr
1209 2912 3980 0.7317 0.6675
MCF7 Dasatinib
0.04
uM
LJP5
2
D06
72
hr
1209 3368 4252 0.7920 0.7587
MCF7 Dasatinib
0.04
uM
LJP5
3
D06
72
hr
1209 3338 4376 0.7628 0.7284
MCF7 Dasatinib
1.11
uM
LJP5
3
D03
72
hr
1209 1581 4376 0.3613 0.1553
MCF7 Seliciclib
0.04
uM
LJP5
2
J06
72
hr
1209 4768 4252 1.1211 1.1301
MCF7 Dasatinib
3.33
uM
LJP5
3
D02
72
hr
1209 1652 4376 0.3775 0.1830
MCF7 Dasatinib
0.12
uM
LJP5
1
D05
72
hr
1209 2313 3980 0.5812 0.4583
MCF7 Dasatinib
0.12
uM
LJP5
2
D05
72
hr
1209 2272 4252 0.5342 0.4156
MCF7 Dasatinib
0.12
uM
LJP5
3
D05
72
hr
1209 2190 4376 0.5004 0.3771
MCF7 Seliciclib
0.37
uM
LJP5
2
J04
72
hr
1209 3832 4252 0.9011 0.8884
MCF7 Tozasertib
0.04
uM
LJP5
3
B18
72
hr
1209 1362 4376 0.3112 0.0661
MCF7 Tozasertib
0.12
uM
LJP5
1
B17
72
hr
1209 1346 3980 0.3382 0.0642
MCF7 Dasatinib
0.37
uM
LJP5
1
D04
72
hr
1209 1693 3980 0.4254 0.2161
MCF7 Dasatinib
0.37
uM
LJP5
2
D04
72
hr
1209 1686 4252 0.3965 0.2009
MCF7 Dasatinib
0.37
uM
LJP5
3
D04
72
hr
1209 1529 4376 0.3494 0.1347
MCF7 Tozasertib
0.37
uM
LJP5
2
B16
72
hr
1209 1475 4252 0.3468 0.1156
MCF7 Seliciclib
10
uM
LJP5
2
J01
72
hr
1209 1273 4252 0.2993 0.0286
MCF7 Tozasertib
3.33
uM
LJP5
1
B14
72
hr
1209 1439 3980 0.3616 0.1064
MCF7 Dasatinib
1.11
uM
LJP5
1
D03
72
hr
1209 1390 3980 0.3492 0.0843
MCF7 AZD-6482
0.12
uM
LJP5
2
I05
72
hr
1209 3945 4252 0.9276 0.9189
MCF7 AZD-6482
0.12
uM
LJP5
1
I05
72
hr
1209 3991 3980 1.0027 1.0032