LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 765 | 218 | 3140 | 0.0694 | -0.4600 |
| BT-20 | A443654 | 10 | uM | LJP6 | 1 | I19 | 72 | hr | 1334 | 219 | 3955 | 0.0554 | -0.6843 |
| Hs 578T | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 765 | 219 | 3095 | 0.0707 | -0.4622 |
| BT-20 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1334 | 219 | 3955 | 0.0554 | -0.6843 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 765 | 223 | 3143 | 0.0709 | -0.4537 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1694 | 224 | 11220 | 0.0200 | -0.5238 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP6 | 3 | C20 | 72 | hr | 765 | 225 | 3066 | 0.0734 | -0.4572 |
| BT-20 | GSK1059615 | 10 | uM | LJP6 | 1 | C01 | 72 | hr | 1334 | 228 | 3955 | 0.0576 | -0.6761 |
| Hs 578T | WH-4-025 | 10 | uM | LJP5 | 1 | O07 | 72 | hr | 765 | 229 | 3140 | 0.0729 | -0.4468 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 1 | G13 | 72 | hr | 1694 | 231 | 11220 | 0.0206 | -0.5184 |
| Hs 578T | WH-4-025 | 10 | uM | LJP5 | 2 | O07 | 72 | hr | 765 | 231 | 3151 | 0.0733 | -0.4436 |
| BT-20 | A443654 | 10 | uM | LJP6 | 2 | I19 | 72 | hr | 1334 | 233 | 3899 | 0.0598 | -0.6765 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 2543 | 239 | 5557 | 0.0430 | -0.8772 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 765 | 240 | 3095 | 0.0775 | -0.4372 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP6 | 2 | C20 | 72 | hr | 765 | 243 | 3095 | 0.0785 | -0.4338 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 2 | G13 | 72 | hr | 1694 | 244 | 11309 | 0.0216 | -0.5072 |
| Hs 578T | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 765 | 246 | 3066 | 0.0802 | -0.4325 |
| BT-20 | A443654 | 10 | uM | LJP6 | 3 | I19 | 72 | hr | 1334 | 246 | 3921 | 0.0627 | -0.6630 |
| Hs 578T | A443654 | 10 | uM | LJP6 | 1 | I19 | 72 | hr | 765 | 246 | 3143 | 0.0783 | -0.4268 |
| Hs 578T | A443654 | 10 | uM | LJP6 | 3 | I19 | 72 | hr | 765 | 247 | 3066 | 0.0806 | -0.4314 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 3 | G13 | 72 | hr | 1694 | 248 | 11121 | 0.0223 | -0.5073 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1334 | 251 | 3955 | 0.0635 | -0.6556 |
| Hs 578T | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 765 | 253 | 3143 | 0.0805 | -0.4188 |
| BT-20 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1334 | 254 | 3955 | 0.0642 | -0.6530 |
| MCF 10A | CGP60474 | 0.12 | uM | LJP6 | 1 | G05 | 72 | hr | 1694 | 255 | 11220 | 0.0227 | -0.5006 |