LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 765 2879 3151 0.9135 0.9133
Hs 578T Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 765 2524 3140 0.8037 0.7966
SK-BR-3 Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 2543 5106 5761 0.8862 0.8054
SK-BR-3 Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 2543 5624 5760 0.9762 0.9596
MCF7 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 1389 3241 6038 0.5367 0.4913
SK-BR-3 Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 2543 5169 5734 0.9014 0.8306
SK-BR-3 Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 2543 4829 5734 0.8421 0.7274
MCF7 Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 1389 4551 6038 0.7537 0.7502
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 1311 5131 5128 1.0005 1.0005
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 1311 4546 5100 0.8914 0.8860
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 1311 4599 5010 0.9178 0.9132
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 1311 4525 5128 0.8824 0.8767
MDA-MB-231 Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 1311 3606 5128 0.7032 0.6721
BT-20 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1334 3325 4117 0.8075 0.7535
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 1311 4607 5100 0.9033 0.8989
MDA-MB-231 Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 1311 3384 5100 0.6635 0.6222
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 1311 4980 5010 0.9938 0.9936
MCF7 Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 1389 4316 5772 0.7477 0.7361
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1311 5167 5010 1.0312 1.0320
SK-BR-3 Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 2543 5129 5761 0.8902 0.8123
SK-BR-3 Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 2543 3520 5760 0.6110 0.3172
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1311 5059 5128 0.9865 0.9862
MDA-MB-231 Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 1311 3505 5010 0.6995 0.6625
Hs 578T Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 765 2966 3140 0.9445 0.9447
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 1311 5327 5010 1.0631 1.0643