LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 3 | N01 | 72 | hr | 2543 | 739 | 5557 | 0.1330 | -0.6658 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 2543 | 769 | 5438 | 0.1414 | -0.6642 |
| BT-20 | A443654 | 10 | uM | LJP6 | 3 | I19 | 72 | hr | 1334 | 246 | 3921 | 0.0627 | -0.6630 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1334 | 251 | 3955 | 0.0635 | -0.6556 |
| BT-20 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1334 | 254 | 3955 | 0.0642 | -0.6530 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1694 | 99 | 11220 | 0.0088 | -0.6470 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 2543 | 863 | 5258 | 0.1641 | -0.6435 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1694 | 106 | 11309 | 0.0094 | -0.6365 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP6 | 2 | G01 | 72 | hr | 2543 | 840 | 5438 | 0.1545 | -0.6360 |
| SK-BR-3 | Alvocidib | 10 | uM | LJP6 | 3 | A13 | 72 | hr | 2543 | 819 | 5557 | 0.1474 | -0.6339 |
| SK-BR-3 | Alvocidib | 10 | uM | LJP6 | 1 | A13 | 72 | hr | 2543 | 902 | 5258 | 0.1715 | -0.6281 |
| BT-20 | Alvocidib | 10 | uM | LJP6 | 2 | A13 | 72 | hr | 1334 | 290 | 3899 | 0.0744 | -0.6273 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 2543 | 910 | 5258 | 0.1730 | -0.6250 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 3 | J01 | 72 | hr | 2543 | 850 | 5557 | 0.1530 | -0.6217 |
| SK-BR-3 | A443654 | 10 | uM | LJP6 | 1 | I19 | 72 | hr | 2543 | 921 | 5258 | 0.1751 | -0.6207 |
| BT-20 | GSK1059615 | 3.33 | uM | LJP6 | 1 | C02 | 72 | hr | 1334 | 295 | 3955 | 0.0746 | -0.6183 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 1 | A17 | 72 | hr | 2543 | 931 | 5258 | 0.1770 | -0.6167 |
| BT-20 | Alvocidib | 10 | uM | LJP6 | 3 | A13 | 72 | hr | 1334 | 302 | 3921 | 0.0770 | -0.6155 |
| BT-20 | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 1334 | 308 | 3899 | 0.0790 | -0.6125 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 3 | G02 | 72 | hr | 1334 | 307 | 3921 | 0.0783 | -0.6114 |
| BT-20 | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 1334 | 310 | 3930 | 0.0789 | -0.6081 |
| SK-BR-3 | BMS345541 | 10 | uM | LJP6 | 1 | D01 | 72 | hr | 2543 | 954 | 5258 | 0.1814 | -0.6077 |
| SK-BR-3 | Alvocidib | 10 | uM | LJP6 | 2 | A13 | 72 | hr | 2543 | 915 | 5438 | 0.1683 | -0.6064 |
| BT-20 | CGP60474 | 10 | uM | LJP6 | 2 | G01 | 72 | hr | 1334 | 316 | 3899 | 0.0810 | -0.6060 |
| BT-20 | CGP60474 | 10 | uM | LJP5 | 2 | F01 | 72 | hr | 1334 | 301 | 4051 | 0.0743 | -0.6054 |