LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 3 | I21 | 72 | hr | 2543 | 1212 | 5557 | 0.2181 | -0.4818 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 1 | G03 | 72 | hr | 1694 | 283 | 11220 | 0.0252 | -0.4811 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1694 | 286 | 11121 | 0.0257 | -0.4807 |
| Hs 578T | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 765 | 205 | 3095 | 0.0662 | -0.4795 |
| SK-BR-3 | AZD7762 | 10 | uM | LJP6 | 3 | L01 | 72 | hr | 2543 | 1218 | 5557 | 0.2192 | -0.4795 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 3 | F01 | 72 | hr | 1389 | 348 | 6038 | 0.0576 | -0.4795 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 1 | D24 | 72 | hr | 2543 | 1183 | 5734 | 0.2063 | -0.4793 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP6 | 1 | G04 | 72 | hr | 1694 | 286 | 11220 | 0.0255 | -0.4791 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1694 | 287 | 11220 | 0.0256 | -0.4785 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP6 | 1 | G04 | 72 | hr | 2543 | 1289 | 5258 | 0.2451 | -0.4772 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 1 | D23 | 72 | hr | 2543 | 1189 | 5734 | 0.2073 | -0.4771 |
| MCF 10A | SNS-032 | 3.33 | uM | LJP6 | 2 | H14 | 72 | hr | 1694 | 287 | 11309 | 0.0254 | -0.4771 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 2 | A17 | 72 | hr | 2543 | 1251 | 5438 | 0.2300 | -0.4765 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 2 | I20 | 72 | hr | 2543 | 1251 | 5438 | 0.2300 | -0.4765 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 1 | I23 | 72 | hr | 2543 | 1291 | 5258 | 0.2455 | -0.4764 |
| BT-20 | Omipalisib | 10 | uM | LJP6 | 3 | N01 | 72 | hr | 1334 | 488 | 3921 | 0.1245 | -0.4764 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 2 | I22 | 72 | hr | 2543 | 1253 | 5438 | 0.2304 | -0.4758 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP5 | 1 | F04 | 72 | hr | 2543 | 1193 | 5734 | 0.2080 | -0.4756 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 3 | H15 | 72 | hr | 1694 | 294 | 11121 | 0.0264 | -0.4754 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 2 | L02 | 72 | hr | 2543 | 1256 | 5438 | 0.2310 | -0.4746 |
| Hs 578T | CGP60474 | 10 | uM | LJP6 | 2 | G01 | 72 | hr | 765 | 209 | 3095 | 0.0675 | -0.4745 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP6 | 1 | C02 | 72 | hr | 2543 | 1296 | 5258 | 0.2464 | -0.4745 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 1 | F03 | 72 | hr | 1389 | 371 | 5772 | 0.0643 | -0.4740 |
| SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 1 | H16 | 72 | hr | 2543 | 1299 | 5258 | 0.2470 | -0.4733 |
| MCF 10A | Alvocidib | 10 | uM | LJP6 | 3 | A13 | 72 | hr | 1694 | 298 | 11121 | 0.0268 | -0.4728 |