LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HG-5-113-01 | 0.12 | uM | LJP5 | 3 | B11 | 72 | hr | 1389 | 4572 | 6038 | 0.7571 | 0.7540 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1389 | 4974 | 5772 | 0.8617 | 0.8602 |
| MCF7 | HG-5-113-01 | 1.11 | uM | LJP5 | 1 | B09 | 72 | hr | 1389 | 2186 | 5772 | 0.3787 | 0.2469 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 1389 | 5915 | 5772 | 1.0247 | 1.0239 |
| MCF7 | HG-5-113-01 | 3.33 | uM | LJP5 | 1 | B08 | 72 | hr | 1389 | 1569 | 5772 | 0.2718 | 0.0611 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1389 | 5578 | 6038 | 0.9237 | 0.9266 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1389 | 6077 | 6038 | 1.0064 | 1.0060 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1389 | 6115 | 6038 | 1.0127 | 1.0119 |
| MCF7 | CP466722 | 0.04 | uM | LJP5 | 3 | I12 | 72 | hr | 1389 | 6478 | 6038 | 1.0728 | 1.0674 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 1 | J02 | 72 | hr | 1389 | 4584 | 5772 | 0.7941 | 0.7878 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 1 | I10 | 72 | hr | 1389 | 5718 | 5772 | 0.9906 | 0.9908 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 1 | I09 | 72 | hr | 1389 | 5905 | 5772 | 1.0230 | 1.0222 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 3 | I09 | 72 | hr | 1389 | 6008 | 6038 | 0.9950 | 0.9952 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1389 | 5104 | 6038 | 0.8452 | 0.8475 |
| MCF7 | CP466722 | 10 | uM | LJP5 | 3 | I07 | 72 | hr | 1389 | 6325 | 6038 | 1.0474 | 1.0442 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 1 | J04 | 72 | hr | 1389 | 5231 | 5772 | 0.9062 | 0.9064 |
| MCF7 | CP724714 | 0.04 | uM | LJP5 | 3 | A12 | 72 | hr | 1389 | 5230 | 6038 | 0.8661 | 0.8689 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1389 | 1149 | 5772 | 0.1991 | -0.0882 |
| MCF7 | CP724714 | 0.37 | uM | LJP5 | 1 | A10 | 72 | hr | 1389 | 4545 | 5772 | 0.7874 | 0.7804 |
| MCF7 | CP724714 | 0.37 | uM | LJP5 | 3 | A10 | 72 | hr | 1389 | 4700 | 6038 | 0.7783 | 0.7770 |
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 1 | A09 | 72 | hr | 1389 | 4828 | 5772 | 0.8364 | 0.8335 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 1389 | 1407 | 6038 | 0.2330 | 0.0061 |
| MCF7 | CP724714 | 10 | uM | LJP5 | 3 | A07 | 72 | hr | 1389 | 3722 | 6038 | 0.6164 | 0.5919 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1389 | 3724 | 6038 | 0.6167 | 0.5923 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1389 | 3750 | 5772 | 0.6496 | 0.6213 |