LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 1 | M18 | 72 | hr | 1476 | 2803 | 3413 | 0.8212 | 0.6992 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 2 | M17 | 72 | hr | 1476 | 2576 | 3783 | 0.6809 | 0.5067 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 2 | M15 | 72 | hr | 1235 | 1306 | 4070 | 0.3209 | 0.0328 |
| MCF7 | ZSTK474 | 10 | uM | LJP6 | 3 | M13 | 72 | hr | 1235 | 1327 | 4126 | 0.3216 | 0.0420 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 1 | M17 | 72 | hr | 1476 | 2249 | 3413 | 0.6589 | 0.4163 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 1 | M17 | 72 | hr | 1235 | 2563 | 3974 | 0.6449 | 0.5418 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 1 | M16 | 72 | hr | 1235 | 1644 | 3974 | 0.4137 | 0.1847 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 1 | M15 | 72 | hr | 1235 | 1385 | 3974 | 0.3485 | 0.0702 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 2 | M14 | 72 | hr | 1235 | 1231 | 4070 | 0.3024 | -0.0021 |
| MCF7 | ZSTK474 | 10 | uM | LJP6 | 2 | M13 | 72 | hr | 1235 | 1220 | 4070 | 0.2997 | -0.0073 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 2 | M18 | 72 | hr | 1476 | 3246 | 3783 | 0.8579 | 0.7865 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 3 | M18 | 72 | hr | 1476 | 3223 | 3734 | 0.8631 | 0.7917 |
| MCF7 | ZSTK474 | 0.04 | uM | LJP6 | 2 | M18 | 72 | hr | 1235 | 3175 | 4070 | 0.7800 | 0.7311 |
| MCF7 | ZSTK474 | 0.04 | uM | LJP6 | 3 | M18 | 72 | hr | 1235 | 3183 | 4126 | 0.7714 | 0.7228 |
| MCF7 | ZSTK474 | 0.04 | uM | LJP6 | 1 | M18 | 72 | hr | 1235 | 3632 | 3974 | 0.9139 | 0.8960 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 3 | M17 | 72 | hr | 1235 | 2395 | 4126 | 0.5804 | 0.4630 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 2 | M16 | 72 | hr | 1235 | 1491 | 4070 | 0.3663 | 0.1155 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 3 | M16 | 72 | hr | 1235 | 1563 | 4126 | 0.3788 | 0.1448 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 3 | M15 | 72 | hr | 1235 | 1322 | 4126 | 0.3204 | 0.0397 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 1 | M14 | 72 | hr | 1235 | 1362 | 3974 | 0.3427 | 0.0596 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 3 | M14 | 72 | hr | 1235 | 1218 | 4126 | 0.2952 | -0.0081 |
| MCF7 | ZSTK474 | 10 | uM | LJP6 | 1 | M13 | 72 | hr | 1235 | 1469 | 3974 | 0.3696 | 0.1082 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 2 | M17 | 72 | hr | 1235 | 1919 | 4070 | 0.4715 | 0.2918 |
| SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 1 | M16 | 72 | hr | 1476 | 1796 | 3413 | 0.5262 | 0.1758 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 3 | M17 | 72 | hr | 1476 | 2480 | 3734 | 0.6642 | 0.4731 |