LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 929 | 4036 | 3185 | 1.2671 | 1.2850 |
| Hs 578T | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 929 | 3925 | 3185 | 1.2323 | 1.2494 |
| Hs 578T | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 929 | 3696 | 3185 | 1.1604 | 1.1746 |
| Hs 578T | Sorafenib | 0.37 | uM | LJP6 | 1 | B10 | 72 | hr | 929 | 3928 | 3185 | 1.2332 | 1.2504 |
| Hs 578T | AZD8055 | 0.37 | uM | LJP6 | 1 | A10 | 72 | hr | 929 | 1235 | 3185 | 0.3877 | 0.1736 |
| Hs 578T | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 929 | 1211 | 3185 | 0.3802 | 0.1607 |
| Hs 578T | AZD8055 | 0.04 | uM | LJP6 | 1 | A12 | 72 | hr | 929 | 1471 | 3185 | 0.4618 | 0.2949 |
| Hs 578T | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 929 | 1084 | 3185 | 0.3403 | 0.0905 |
| Hs 578T | AZD7762 | 10 | uM | LJP6 | 1 | L01 | 72 | hr | 929 | 696 | 3185 | 0.2185 | -0.1501 |
| Hs 578T | Sorafenib | 0.12 | uM | LJP6 | 1 | B11 | 72 | hr | 929 | 3814 | 3185 | 1.1974 | 1.2134 |
| Hs 578T | AZD8055 | 0.12 | uM | LJP6 | 1 | A11 | 72 | hr | 929 | 1262 | 3185 | 0.3962 | 0.1879 |
| Hs 578T | AZD7762 | 0.37 | uM | LJP6 | 1 | L04 | 72 | hr | 929 | 1163 | 3185 | 0.3651 | 0.1346 |
| Hs 578T | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 929 | 1250 | 3185 | 0.3924 | 0.1816 |
| Hs 578T | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 929 | 2750 | 3185 | 0.8634 | 0.8413 |
| Hs 578T | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 929 | 923 | 3185 | 0.2898 | -0.0038 |
| Hs 578T | AZD7762 | 0.12 | uM | LJP6 | 1 | L05 | 72 | hr | 929 | 1201 | 3185 | 0.3771 | 0.1553 |
| Hs 578T | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 929 | 662 | 3185 | 0.2078 | -0.1737 |
| Hs 578T | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 929 | 897 | 3185 | 0.2816 | -0.0197 |
| Hs 578T | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 929 | 731 | 3185 | 0.2295 | -0.1263 |
| Hs 578T | AZD7762 | 0.04 | uM | LJP6 | 1 | L06 | 72 | hr | 929 | 1738 | 3185 | 0.5457 | 0.4223 |
| Hs 578T | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 929 | 1018 | 3185 | 0.3196 | 0.0527 |
| Hs 578T | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 929 | 866 | 3185 | 0.2719 | -0.0389 |
| Hs 578T | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 929 | 3195 | 3185 | 1.0031 | 1.0035 |
| Hs 578T | Alvocidib | 0.04 | uM | LJP6 | 1 | A18 | 72 | hr | 929 | 2307 | 3185 | 0.7243 | 0.6680 |
| Hs 578T | Sorafenib | 10 | uM | LJP6 | 1 | B07 | 72 | hr | 929 | 2959 | 3185 | 0.9290 | 0.9188 |