LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 1 | D12 | 72 | hr | 1476 | 4380 | 3413 | 1.2832 | 1.4583 |
| SK-BR-3 | R406 | 1.11 | uM | LJP6 | 1 | C15 | 72 | hr | 1476 | 4281 | 3413 | 1.2542 | 1.4122 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 1 | D11 | 72 | hr | 1476 | 4261 | 3413 | 1.2484 | 1.4029 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1476 | 4824 | 3788 | 1.2733 | 1.3890 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1476 | 4212 | 3413 | 1.2340 | 1.3800 |
| MCF7 | LJP6 | 1 | J13 | 72 | hr | 1235 | 5294 | 3974 | 1.3321 | 1.3709 | |||
| SK-BR-3 | LJP6 | 1 | F09 | 72 | hr | 1476 | 4187 | 3413 | 1.2267 | 1.3683 | |||
| MCF7 | LJP5 | 1 | J13 | 72 | hr | 1235 | 5461 | 4119 | 1.3257 | 1.3524 | |||
| SK-BR-3 | LJP5 | 2 | F11 | 72 | hr | 1476 | 4634 | 3731 | 1.2420 | 1.3518 | |||
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 3 | I12 | 72 | hr | 1476 | 4626 | 3734 | 1.2389 | 1.3471 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 1476 | 4124 | 3413 | 1.2082 | 1.3388 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 1 | I09 | 72 | hr | 1476 | 4124 | 3413 | 1.2082 | 1.3388 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 1 | I10 | 72 | hr | 1476 | 4059 | 3413 | 1.1892 | 1.3082 |
| SK-BR-3 | LJP5 | 3 | F07 | 72 | hr | 1476 | 4613 | 3796 | 1.2150 | 1.3074 | |||
| BT-20 | PD173074 | 3.33 | uM | LJP6 | 2 | I08 | 72 | hr | 1657 | 6819 | 5360 | 1.2722 | 1.3056 |
| SK-BR-3 | LJP5 | 2 | F10 | 72 | hr | 1476 | 4506 | 3731 | 1.2076 | 1.3031 | |||
| SK-BR-3 | LJP5 | 2 | F07 | 72 | hr | 1476 | 4504 | 3731 | 1.2071 | 1.3023 | |||
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 1 | G10 | 72 | hr | 1476 | 4585 | 3788 | 1.2102 | 1.3014 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 1 | G08 | 72 | hr | 1476 | 4575 | 3788 | 1.2076 | 1.2977 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 1 | I11 | 72 | hr | 1476 | 4032 | 3413 | 1.1813 | 1.2955 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 3 | I11 | 72 | hr | 1476 | 4486 | 3734 | 1.2014 | 1.2938 |
| SK-BR-3 | LJP5 | 2 | F09 | 72 | hr | 1476 | 4478 | 3731 | 1.2001 | 1.2924 | |||
| SK-BR-3 | LJP6 | 1 | F12 | 72 | hr | 1476 | 4025 | 3413 | 1.1792 | 1.2922 | |||
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 1 | K04 | 72 | hr | 1476 | 4559 | 3788 | 1.2033 | 1.2918 |
| MCF7 | Gefitinib | 0.37 | uM | LJP6 | 1 | N10 | 72 | hr | 1235 | 4997 | 3974 | 1.2574 | 1.2911 |