High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 470 | 334 | | 17082 | 34713 | 121.5 | 40.86 | 150.26 | 149.90 | 78 | 87 | 96 | 104 | 113 | 124 | 137 | 153 | 176 | 0.0613 | 2127 | 0.917 | 53.45 | 21.26 | 5 | 0.0091 | 155 | 0.0008 | 47.08 | 7.438 | 0.1848 | 16426.1 | 2470000 | 412000000 | 75400000000 | 0.5115 | 0.1584 | 0.0012 | 0.0001 | 0.0040 | 0.0001 | 0.0120 | 0.0016 | 0.0473 | 0.0092 | 0.1219 | 0.0386 | 0.1808 | 0.0802 | 0.1691 | 0.0807 | 0.1727 | 0.1152 | 0.2911 | 0.6742 | 0.0005 | 0.0001 | 0.0019 | 0.0001 | 0.0033 | 0.0009 | 0.0140 | 0.0056 | 0.0416 | 0.0205 | 0.0689 | 0.0420 | 0.0618 | 0.0336 | 0.0900 | 0.0533 | 0.7179 | 0.8439 | 0.0012 | 0.0043 | 0.0043 | 0.0104 | 0.0127 | 0.0293 | 0.0437 | 0.0804 | 0.1009 | 0.1268 | 0.1386 | 0.1608 | 0.1105 | 0.1154 | 0.1410 | 0.1334 | 0.4469 | 0.3392 | 0.0011 | 0.0023 | 0.0098 | 0.0256 | 0.0655 | 0.1021 | 0.0917 | 0.1081 | 0.5939 | 13 | 20 | 40 | 73 | 109 | 146 | 192 | 255 | 354 | 0.0246 | 17.30 | 5.572 | 0.4804 | 45049.4 | 19600000 | 11700000000 | 9560000000000 | 0.5599 | 0.1198 | 0.0163 | 0.0018 | 0.0736 | 0.0061 | 0.1603 | 0.0328 | 0.1540 | 0.0660 | 0.1820 | 0.1370 | 0.1647 | 0.1862 | 0.1066 | 0.1461 | 0.0830 | 0.1520 | 0.0595 | 0.2718 | 0.0002 | 0.0004 | 0.0015 | 0.0006 | 0.0032 | 0.0019 | 0.0118 | 0.0080 | 0.0480 | 0.0350 | 0.0826 | 0.0652 | 0.0678 | 0.0531 | 0.0929 | 0.0754 | 0.6920 | 0.7604 | 0.0006 | 0.0013 | 0.0019 | 0.0026 | 0.0068 | 0.0081 | 0.0218 | 0.0295 | 0.0745 | 0.0894 | 0.1255 | 0.1446 | 0.0963 | 0.1068 | 0.1258 | 0.1351 | 0.5468 | 0.4826 | 0.0005 | 0.0014 | 0.0039 | 0.0169 | 0.0590 | 0.1040 | 0.0801 | 0.1148 | 0.6194 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 736 | 857 | | 16963 | 12738 | 140.2 | 47.70 | 284.47 | 272.42 | 86 | 103 | 115 | 125 | 135 | 146 | 159 | 175 | 199 | 0.1170 | 1490 | 0.454 | 104.36 | 26.02 | 3 | 0.0222 | 376 | 0.0013 | 28.58 | 7.013 | 0.2392 | 21921.8 | 3810000 | 736000000 | 159000000000 | 0.5138 | 0.1429 | 0.0011 | 0.0001 | 0.0046 | 0.0004 | 0.0190 | 0.0015 | 0.0417 | 0.0061 | 0.1096 | 0.0343 | 0.1753 | 0.0705 | 0.1648 | 0.0732 | 0.1725 | 0.1036 | 0.3113 | 0.7103 | 0.0003 | 0.0000 | 0.0016 | 0.0003 | 0.0030 | 0.0006 | 0.0086 | 0.0019 | 0.0379 | 0.0187 | 0.0685 | 0.0336 | 0.0683 | 0.0292 | 0.0917 | 0.0481 | 0.7201 | 0.8674 | 0.0029 | 0.0048 | 0.0072 | 0.0161 | 0.0144 | 0.0353 | 0.0503 | 0.0744 | 0.1120 | 0.1435 | 0.1511 | 0.1879 | 0.1142 | 0.0969 | 0.1336 | 0.1381 | 0.4144 | 0.3030 | 0.0010 | 0.0034 | 0.0085 | 0.0267 | 0.0777 | 0.1103 | 0.0988 | 0.1250 | 0.5485 | 17 | 30 | 70 | 134 | 213 | 299 | 394 | 506 | 659 | 0.0090 | 99.68 | 6.927 | 0.2797 | 155129.0 | 112000000 | 97700000000 | 101000000000000 | 0.5569 | 0.1416 | 0.0517 | 0.0052 | 0.1626 | 0.0189 | 0.2432 | 0.1060 | 0.1736 | 0.1157 | 0.1416 | 0.1826 | 0.1121 | 0.2064 | 0.0622 | 0.1365 | 0.0296 | 0.1148 | 0.0234 | 0.1139 | 0.0003 | 0.0000 | 0.0024 | 0.0010 | 0.0037 | 0.0030 | 0.0161 | 0.0098 | 0.0690 | 0.0611 | 0.1238 | 0.1119 | 0.0809 | 0.0760 | 0.1129 | 0.1040 | 0.5907 | 0.6331 | 0.0007 | 0.0011 | 0.0042 | 0.0032 | 0.0077 | 0.0122 | 0.0247 | 0.0416 | 0.0967 | 0.1108 | 0.1543 | 0.1728 | 0.1062 | 0.1147 | 0.1406 | 0.1433 | 0.4650 | 0.4004 | 0.0008 | 0.0013 | 0.0077 | 0.0199 | 0.0782 | 0.1419 | 0.0914 | 0.1252 | 0.5336 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1028 | 231 | | 11368 | 9358 | 393.3 | 133.58 | 93.30 | 136.68 | 187 | 274 | 336 | 383 | 422 | 451 | 481 | 509 | 544 | 0.1038 | 971 | 0.530 | 101.02 | 17.03 | 7 | 0.0223 | 254 | 0.0009 | 24.62 | 7.358 | 0.2464 | 172513.0 | 80400000 | 39000000000 | 19500000000000 | 0.5210 | 0.1387 | 0.0011 | 0.0006 | 0.0017 | 0.0005 | 0.0047 | 0.0018 | 0.0170 | 0.0049 | 0.0766 | 0.0277 | 0.1275 | 0.0545 | 0.1031 | 0.0384 | 0.1389 | 0.0594 | 0.5294 | 0.8122 | 0.0000 | 0.0001 | 0.0001 | 0.0001 | 0.0000 | 0.0002 | 0.0023 | 0.0012 | 0.0230 | 0.0184 | 0.0392 | 0.0346 | 0.0241 | 0.0188 | 0.0387 | 0.0285 | 0.8726 | 0.8980 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0061 | 0.0000 | 0.0163 | 0.0000 | 0.0472 | 0.0000 | 0.0674 | 0.0000 | 0.0653 | 0.0000 | 0.0888 | 0.0000 | 0.7054 | 1.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0047 | 0.0314 | 0.0487 | 0.0382 | 0.0542 | 0.8214 | 10 | 12 | 15 | 20 | 34 | 52 | 79 | 150 | 276 | 0.1156 | 10.49 | 4.045 | 0.6216 | 27384.8 | 12500000 | 7130000000 | 4620000000000 | 0.4672 | 0.1594 | 0.0875 | 0.0139 | 0.2611 | 0.0541 | 0.2439 | 0.2073 | 0.1148 | 0.1314 | 0.0933 | 0.1294 | 0.0689 | 0.1208 | 0.0473 | 0.0812 | 0.0445 | 0.0759 | 0.0387 | 0.1861 | 0.0003 | 0.0020 | 0.0031 | 0.0022 | 0.0037 | 0.0053 | 0.0252 | 0.0193 | 0.0857 | 0.0735 | 0.1244 | 0.1092 | 0.0857 | 0.0732 | 0.1163 | 0.1151 | 0.5556 | 0.6003 | 0.0000 | 0.0000 | 0.0004 | 0.0010 | 0.0045 | 0.0077 | 0.0254 | 0.0305 | 0.0994 | 0.1056 | 0.1582 | 0.1608 | 0.0856 | 0.0944 | 0.1270 | 0.1370 | 0.4996 | 0.4630 | 0.0008 | 0.0044 | 0.0044 | 0.0252 | 0.0913 | 0.1442 | 0.0873 | 0.1197 | 0.5226 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 448 | 583 | | 4870 | 11803 | 145.2 | 35.55 | 166.28 | 141.22 | 106 | 119 | 129 | 136 | 143 | 150 | 157 | 166 | 182 | 0.0848 | 1001 | 1.080 | 90.80 | 26.02 | 1 | 0.0448 | 218 | 0.0023 | 21.25 | 6.376 | 0.2593 | 22352.9 | 3700000 | 674000000 | 140000000000 | 0.5233 | 0.1537 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0063 | 0.0020 | 0.0186 | 0.0059 | 0.0714 | 0.0204 | 0.1461 | 0.0576 | 0.1467 | 0.0492 | 0.1833 | 0.0730 | 0.4263 | 0.7916 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0017 | 0.0013 | 0.0087 | 0.0044 | 0.0397 | 0.0176 | 0.0788 | 0.0439 | 0.0694 | 0.0279 | 0.1031 | 0.0468 | 0.6983 | 0.8580 | 0.0071 | 0.0138 | 0.0228 | 0.0276 | 0.0342 | 0.0369 | 0.1198 | 0.1244 | 0.1641 | 0.1982 | 0.1897 | 0.1935 | 0.1227 | 0.0599 | 0.1098 | 0.1152 | 0.2297 | 0.2304 | 0.0030 | 0.0056 | 0.0155 | 0.0494 | 0.0975 | 0.1375 | 0.1224 | 0.1538 | 0.4154 | 18 | 39 | 68 | 100 | 133 | 170 | 213 | 270 | 362 | 0.0037 | 57.89 | 6.920 | 0.2988 | 47591.3 | 18100000 | 8370000000 | 4450000000000 | 0.4521 | 0.1774 | 0.0099 | 0.0010 | 0.0727 | 0.0018 | 0.1824 | 0.0223 | 0.1760 | 0.0674 | 0.2042 | 0.1490 | 0.1715 | 0.2039 | 0.0989 | 0.1663 | 0.0578 | 0.1655 | 0.0267 | 0.2229 | 0.0002 | 0.0000 | 0.0010 | 0.0008 | 0.0039 | 0.0034 | 0.0108 | 0.0072 | 0.0510 | 0.0340 | 0.0877 | 0.0683 | 0.0730 | 0.0617 | 0.1087 | 0.0831 | 0.6637 | 0.7415 | 0.0013 | 0.0019 | 0.0013 | 0.0061 | 0.0077 | 0.0145 | 0.0286 | 0.0352 | 0.0848 | 0.1044 | 0.1358 | 0.1322 | 0.1054 | 0.1131 | 0.1247 | 0.1251 | 0.5106 | 0.4674 | 0.0006 | 0.0029 | 0.0045 | 0.0181 | 0.0642 | 0.1082 | 0.0990 | 0.1199 | 0.5826 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1018 | 411 | | 2600 | 6088 | 103.7 | 24.69 | 101.32 | 87.25 | 73 | 84 | 90 | 96 | 102 | 108 | 114 | 122 | 135 | 0.1304 | 794 | 0.757 | 122.10 | 28.23 | 2 | 0.1200 | 312 | 0.0039 | 11.20 | 5.825 | 0.3318 | 11365.0 | 1320000 | 161000000 | 21000000000 | 0.5268 | 0.1497 | 0.0006 | 0.0000 | 0.0037 | 0.0004 | 0.0141 | 0.0012 | 0.0263 | 0.0050 | 0.0912 | 0.0308 | 0.1769 | 0.0791 | 0.1622 | 0.0579 | 0.1714 | 0.0991 | 0.3537 | 0.7265 | 0.0005 | 0.0000 | 0.0014 | 0.0004 | 0.0038 | 0.0008 | 0.0100 | 0.0031 | 0.0491 | 0.0212 | 0.0920 | 0.0586 | 0.0734 | 0.0358 | 0.0972 | 0.0657 | 0.6725 | 0.8144 | 0.0043 | 0.0071 | 0.0259 | 0.0496 | 0.0237 | 0.0567 | 0.1034 | 0.1064 | 0.1315 | 0.2199 | 0.1810 | 0.1348 | 0.1099 | 0.1277 | 0.1142 | 0.1064 | 0.3060 | 0.1915 | 0.0033 | 0.0033 | 0.0181 | 0.0280 | 0.0954 | 0.1151 | 0.1127 | 0.1332 | 0.4910 | 24 | 33 | 44 | 57 | 72 | 91 | 120 | 163 | 222 | 0.0127 | 11.75 | 5.310 | 0.4411 | 17878.5 | 4610000 | 1580000000 | 681000000000 | 0.5373 | 0.1316 | 0.0246 | 0.0041 | 0.1026 | 0.0157 | 0.2041 | 0.0508 | 0.1688 | 0.1015 | 0.1709 | 0.1614 | 0.1368 | 0.1756 | 0.0887 | 0.1558 | 0.0641 | 0.1355 | 0.0395 | 0.1995 | 0.0022 | 0.0020 | 0.0051 | 0.0055 | 0.0091 | 0.0086 | 0.0215 | 0.0204 | 0.0680 | 0.0540 | 0.1066 | 0.0870 | 0.0844 | 0.0804 | 0.1135 | 0.1042 | 0.5897 | 0.6380 | 0.0022 | 0.0013 | 0.0039 | 0.0053 | 0.0061 | 0.0112 | 0.0259 | 0.0258 | 0.0783 | 0.0998 | 0.1517 | 0.1685 | 0.0998 | 0.1005 | 0.1224 | 0.1375 | 0.5097 | 0.4501 | 0.0027 | 0.0032 | 0.0163 | 0.0195 | 0.0736 | 0.1290 | 0.0940 | 0.1154 | 0.5463 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1109 | 791 | | 9893 | 20116 | 97.3 | 34.99 | 152.25 | 139.00 | 59 | 71 | 78 | 85 | 92 | 100 | 109 | 122 | 142 | 0.0680 | 1367 | 0.691 | 64.66 | 21.00 | 2 | 0.0208 | 206 | 0.0011 | 48.57 | 7.180 | 0.2021 | 10687.4 | 1320000 | 184000000 | 28700000000 | 0.5283 | 0.1408 | 0.0017 | 0.0000 | 0.0030 | 0.0003 | 0.0286 | 0.0013 | 0.0650 | 0.0096 | 0.1374 | 0.0448 | 0.1825 | 0.0976 | 0.1668 | 0.0904 | 0.1696 | 0.1321 | 0.2454 | 0.6238 | 0.0009 | 0.0000 | 0.0010 | 0.0001 | 0.0048 | 0.0001 | 0.0158 | 0.0049 | 0.0504 | 0.0240 | 0.0807 | 0.0492 | 0.0728 | 0.0375 | 0.1094 | 0.0633 | 0.6642 | 0.8209 | 0.0008 | 0.0032 | 0.0055 | 0.0144 | 0.0152 | 0.0335 | 0.0601 | 0.0813 | 0.1261 | 0.1491 | 0.1582 | 0.1914 | 0.1290 | 0.1148 | 0.1472 | 0.1260 | 0.3579 | 0.2863 | 0.0016 | 0.0025 | 0.0094 | 0.0338 | 0.0912 | 0.1218 | 0.1065 | 0.1342 | 0.4990 | 16 | 34 | 57 | 83 | 111 | 147 | 192 | 251 | 344 | 0.0118 | 24.15 | 5.952 | 0.3916 | 42501.1 | 16300000 | 7740000000 | 4260000000000 | 0.4988 | 0.1607 | 0.0275 | 0.0011 | 0.1169 | 0.0097 | 0.2130 | 0.0538 | 0.1636 | 0.0856 | 0.1683 | 0.1643 | 0.1424 | 0.1882 | 0.0820 | 0.1427 | 0.0568 | 0.1438 | 0.0296 | 0.2107 | 0.0004 | 0.0003 | 0.0017 | 0.0007 | 0.0039 | 0.0041 | 0.0160 | 0.0085 | 0.0595 | 0.0462 | 0.1060 | 0.0850 | 0.0867 | 0.0678 | 0.1130 | 0.1003 | 0.6127 | 0.6871 | 0.0008 | 0.0017 | 0.0031 | 0.0057 | 0.0093 | 0.0109 | 0.0287 | 0.0382 | 0.0867 | 0.1002 | 0.1526 | 0.1644 | 0.1028 | 0.1095 | 0.1329 | 0.1367 | 0.4830 | 0.4326 | 0.0001 | 0.0023 | 0.0070 | 0.0206 | 0.0702 | 0.1325 | 0.0932 | 0.1236 | 0.5506 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 279 | 429 | | 995 | 12586 | 70.7 | 14.90 | 155.58 | 186.93 | 55 | 59 | 63 | 66 | 69 | 72 | 76 | 81 | 90 | 0.0678 | 853 | 0.399 | 137.53 | 31.00 | 1 | 0.5668 | 564 | 0.0090 | 7.28 | 5.031 | 0.3913 | 5218.8 | 403150 | 32700000 | 2780000000 | 0.5290 | 0.1303 | 0.0014 | 0.0000 | 0.0041 | 0.0000 | 0.0218 | 0.0032 | 0.0476 | 0.0139 | 0.1252 | 0.0586 | 0.1823 | 0.1471 | 0.1469 | 0.0768 | 0.1524 | 0.1333 | 0.3184 | 0.5672 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0020 | 0.0207 | 0.0061 | 0.0794 | 0.0499 | 0.1427 | 0.1314 | 0.0863 | 0.0540 | 0.1116 | 0.0967 | 0.5524 | 0.6599 | 0.0149 | 0.0455 | 0.0149 | 0.0000 | 0.0522 | 0.1136 | 0.1343 | 0.1136 | 0.2015 | 0.2955 | 0.2015 | 0.2045 | 0.1119 | 0.0227 | 0.1269 | 0.1818 | 0.1418 | 0.0227 | 0.0068 | 0.0158 | 0.0158 | 0.0813 | 0.1512 | 0.1558 | 0.1129 | 0.1490 | 0.3115 | 16 | 20 | 30 | 53 | 84 | 116 | 167 | 264 | 418 | 0.0235 | 46.09 | 5.759 | 0.4355 | 59144.7 | 33000000 | 22700000000 | 17700000000000 | 0.5490 | 0.1235 | 0.0353 | 0.0025 | 0.1470 | 0.0151 | 0.2292 | 0.0792 | 0.1425 | 0.1235 | 0.1447 | 0.1704 | 0.1190 | 0.1746 | 0.0816 | 0.1179 | 0.0654 | 0.1193 | 0.0353 | 0.1975 | 0.0004 | 0.0007 | 0.0004 | 0.0019 | 0.0042 | 0.0029 | 0.0129 | 0.0102 | 0.0601 | 0.0507 | 0.1106 | 0.0865 | 0.0811 | 0.0676 | 0.1162 | 0.1025 | 0.6141 | 0.6771 | 0.0009 | 0.0010 | 0.0023 | 0.0017 | 0.0032 | 0.0023 | 0.0227 | 0.0252 | 0.0827 | 0.1026 | 0.1474 | 0.1437 | 0.0903 | 0.1010 | 0.1282 | 0.1400 | 0.5223 | 0.4826 | 0.0002 | 0.0015 | 0.0037 | 0.0187 | 0.0791 | 0.1231 | 0.0843 | 0.1271 | 0.5622 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1246 | 581 | | 5724 | 10893 | 64.5 | 15.39 | 236.73 | 211.09 | 47 | 52 | 56 | 60 | 63 | 66 | 70 | 75 | 83 | 0.1007 | 1097 | 0.634 | 184.57 | 34.06 | 2 | 0.0786 | 450 | 0.0087 | 5.31 | 5.104 | 0.4181 | 4403.3 | 318930 | 24700000 | 2070000000 | 0.5293 | 0.1575 | 0.0011 | 0.0000 | 0.0029 | 0.0002 | 0.0149 | 0.0025 | 0.0344 | 0.0079 | 0.0831 | 0.0249 | 0.1403 | 0.0624 | 0.1470 | 0.0543 | 0.2027 | 0.0933 | 0.3736 | 0.7545 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0073 | 0.0014 | 0.0168 | 0.0048 | 0.0432 | 0.0173 | 0.0852 | 0.0464 | 0.0787 | 0.0324 | 0.1224 | 0.0582 | 0.6454 | 0.8396 | 0.0146 | 0.0251 | 0.0258 | 0.0282 | 0.0538 | 0.0219 | 0.0806 | 0.1066 | 0.1333 | 0.1818 | 0.1445 | 0.1630 | 0.1333 | 0.1348 | 0.1344 | 0.1285 | 0.2800 | 0.2100 | 0.0049 | 0.0125 | 0.0245 | 0.0623 | 0.1061 | 0.1303 | 0.1318 | 0.1477 | 0.3799 | 16 | 25 | 64 | 130 | 196 | 261 | 329 | 412 | 529 | 0.0116 | 86.41 | 6.934 | 0.2713 | 100595.0 | 54000000 | 33700000000 | 23600000000000 | 0.4576 | 0.1893 | 0.0320 | 0.0013 | 0.1436 | 0.0119 | 0.2339 | 0.0569 | 0.1831 | 0.1264 | 0.1737 | 0.1747 | 0.1260 | 0.2062 | 0.0652 | 0.1467 | 0.0332 | 0.1364 | 0.0094 | 0.1396 | 0.0005 | 0.0003 | 0.0027 | 0.0008 | 0.0034 | 0.0019 | 0.0151 | 0.0095 | 0.0589 | 0.0467 | 0.0943 | 0.0811 | 0.0861 | 0.0713 | 0.1289 | 0.1061 | 0.6100 | 0.6824 | 0.0003 | 0.0012 | 0.0025 | 0.0031 | 0.0076 | 0.0127 | 0.0227 | 0.0347 | 0.0882 | 0.1018 | 0.1372 | 0.1535 | 0.1175 | 0.1148 | 0.1447 | 0.1528 | 0.4794 | 0.4254 | 0.0017 | 0.0015 | 0.0040 | 0.0185 | 0.0733 | 0.1092 | 0.0968 | 0.1432 | 0.5521 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1049 | 621 | | 590 | 4448 | 85.8 | 21.32 | 144.11 | 133.60 | 56 | 64 | 73 | 81 | 87 | 93 | 99 | 106 | 114 | 0.1034 | 460 | 0.497 | 89.47 | 17.12 | 2 | 0.4254 | 251 | 0.0059 | 8.91 | 5.340 | 0.3127 | 7819.9 | 748619 | 74600000 | 7680000000 | 0.5406 | 0.1228 | 0.0066 | 0.0000 | 0.0197 | 0.0037 | 0.0656 | 0.0019 | 0.1016 | 0.0335 | 0.1311 | 0.0764 | 0.2557 | 0.1676 | 0.1213 | 0.0950 | 0.1279 | 0.1639 | 0.1705 | 0.4581 | 0.0000 | 0.0000 | 0.0023 | 0.0018 | 0.0023 | 0.0018 | 0.0227 | 0.0161 | 0.0975 | 0.0698 | 0.2245 | 0.1592 | 0.0998 | 0.0823 | 0.1678 | 0.1485 | 0.3832 | 0.5206 | 0.0000 | 0.0000 | 0.0074 | 0.0909 | 0.0662 | 0.1818 | 0.1103 | 0.2273 | 0.1838 | 0.3636 | 0.2721 | 0.0455 | 0.1176 | 0.0909 | 0.0809 | 0.0000 | 0.1618 | 0.0000 | 0.0032 | 0.0130 | 0.0260 | 0.0747 | 0.1494 | 0.1851 | 0.1071 | 0.1558 | 0.2857 | 25 | 39 | 55 | 74 | 98 | 130 | 170 | 228 | 340 | 0.0100 | 16.93 | 5.669 | 0.4305 | 38612.5 | 14500000 | 6620000000 | 3390000000000 | 0.5378 | 0.1265 | 0.0156 | 0.0023 | 0.0845 | 0.0068 | 0.1831 | 0.0288 | 0.1815 | 0.0788 | 0.1800 | 0.1455 | 0.1315 | 0.1856 | 0.0767 | 0.1667 | 0.0610 | 0.1439 | 0.0861 | 0.2417 | 0.0010 | 0.0013 | 0.0036 | 0.0025 | 0.0051 | 0.0033 | 0.0159 | 0.0134 | 0.0568 | 0.0473 | 0.0967 | 0.0854 | 0.0747 | 0.0703 | 0.0988 | 0.1000 | 0.6474 | 0.6766 | 0.0000 | 0.0037 | 0.0038 | 0.0019 | 0.0198 | 0.0131 | 0.0243 | 0.0411 | 0.0654 | 0.0626 | 0.1209 | 0.1280 | 0.0928 | 0.0888 | 0.1042 | 0.1271 | 0.5688 | 0.5336 | 0.0006 | 0.0000 | 0.0112 | 0.0262 | 0.0611 | 0.1185 | 0.0855 | 0.1017 | 0.5951 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1047 | 808 | | 11793 | 29672 | 113.4 | 29.34 | 199.72 | 175.90 | 81 | 89 | 96 | 102 | 108 | 115 | 124 | 135 | 153 | 0.0534 | 1583 | 0.454 | 192.20 | 38.59 | 5 | 0.0484 | 571 | 0.0029 | 15.86 | 6.239 | 0.2893 | 13720.4 | 1780000 | 247000000 | 36900000000 | 0.5494 | 0.1414 | 0.0009 | 0.0000 | 0.0048 | 0.0002 | 0.0148 | 0.0015 | 0.0418 | 0.0067 | 0.0987 | 0.0255 | 0.1564 | 0.0610 | 0.1565 | 0.0585 | 0.1823 | 0.0902 | 0.3439 | 0.7563 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0052 | 0.0007 | 0.0169 | 0.0038 | 0.0447 | 0.0139 | 0.0787 | 0.0369 | 0.0757 | 0.0239 | 0.1044 | 0.0426 | 0.6722 | 0.8779 | 0.0055 | 0.0043 | 0.0115 | 0.0182 | 0.0243 | 0.0503 | 0.0545 | 0.1146 | 0.1261 | 0.1767 | 0.1530 | 0.1734 | 0.1129 | 0.1199 | 0.1500 | 0.1370 | 0.3622 | 0.2056 | 0.0035 | 0.0069 | 0.0125 | 0.0420 | 0.0881 | 0.1219 | 0.1128 | 0.1261 | 0.4861 | 21 | 40 | 70 | 109 | 156 | 208 | 264 | 334 | 444 | 0.0045 | 62.50 | 7.035 | 0.2736 | 70826.1 | 33200000 | 18700000000 | 12000000000000 | 0.4909 | 0.1748 | 0.0241 | 0.0016 | 0.1156 | 0.0080 | 0.2373 | 0.0460 | 0.1905 | 0.1069 | 0.1697 | 0.1785 | 0.1335 | 0.2098 | 0.0719 | 0.1527 | 0.0399 | 0.1470 | 0.0174 | 0.1495 | 0.0004 | 0.0002 | 0.0009 | 0.0011 | 0.0042 | 0.0023 | 0.0126 | 0.0094 | 0.0581 | 0.0468 | 0.1027 | 0.0856 | 0.0862 | 0.0727 | 0.1139 | 0.0958 | 0.6211 | 0.6861 | 0.0010 | 0.0011 | 0.0048 | 0.0062 | 0.0108 | 0.0147 | 0.0306 | 0.0373 | 0.0810 | 0.0966 | 0.1391 | 0.1521 | 0.1107 | 0.1138 | 0.1321 | 0.1356 | 0.4899 | 0.4427 | 0.0002 | 0.0024 | 0.0061 | 0.0189 | 0.0699 | 0.1259 | 0.0994 | 0.1257 | 0.5515 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 880 | 168 | | 38955 | 26240 | 163.7 | 54.42 | 189.84 | 155.38 | 92 | 114 | 132 | 148 | 164 | 179 | 194 | 210 | 233 | 0.1215 | 3188 | 0.799 | 74.95 | 17.03 | 13 | 0.0043 | 168 | 0.0008 | 32.80 | 7.366 | 0.2060 | 29769.9 | 5880000 | 1240000000 | 280000000000 | 0.5763 | 0.1150 | 0.0010 | 0.0002 | 0.0035 | 0.0005 | 0.0154 | 0.0020 | 0.0472 | 0.0094 | 0.1113 | 0.0378 | 0.1741 | 0.0717 | 0.1653 | 0.0787 | 0.1782 | 0.1069 | 0.3041 | 0.6929 | 0.0003 | 0.0001 | 0.0009 | 0.0002 | 0.0030 | 0.0009 | 0.0108 | 0.0048 | 0.0303 | 0.0203 | 0.0519 | 0.0341 | 0.0512 | 0.0327 | 0.0704 | 0.0446 | 0.7812 | 0.8624 | 0.0018 | 0.0076 | 0.0072 | 0.0135 | 0.0124 | 0.0327 | 0.0413 | 0.0819 | 0.0859 | 0.1325 | 0.1267 | 0.1726 | 0.1108 | 0.1197 | 0.1380 | 0.1307 | 0.4759 | 0.3088 | 0.0012 | 0.0016 | 0.0058 | 0.0209 | 0.0477 | 0.0807 | 0.0801 | 0.1009 | 0.6610 | 30 | 51 | 77 | 110 | 148 | 191 | 245 | 316 | 419 | 0.0043 | 23.31 | 6.446 | 0.3390 | 60178.8 | 24700000 | 11900000000 | 6310000000000 | 0.6103 | 0.0987 | 0.0154 | 0.0035 | 0.0720 | 0.0118 | 0.1491 | 0.0312 | 0.1825 | 0.0787 | 0.1846 | 0.1419 | 0.1799 | 0.1989 | 0.0982 | 0.1547 | 0.0673 | 0.1582 | 0.0509 | 0.2210 | 0.0009 | 0.0008 | 0.0043 | 0.0023 | 0.0067 | 0.0044 | 0.0211 | 0.0165 | 0.0660 | 0.0589 | 0.1135 | 0.1002 | 0.0823 | 0.0792 | 0.1052 | 0.1029 | 0.6000 | 0.6347 | 0.0009 | 0.0028 | 0.0066 | 0.0068 | 0.0095 | 0.0154 | 0.0324 | 0.0388 | 0.0825 | 0.0887 | 0.1348 | 0.1364 | 0.0914 | 0.0993 | 0.1153 | 0.1173 | 0.5266 | 0.4944 | 0.0018 | 0.0040 | 0.0100 | 0.0258 | 0.0759 | 0.1202 | 0.0937 | 0.1112 | 0.5575 |